Evidence map›Paper›PMID 40704401›Full record

Observational studyMovement disorders clinical practice2026

Profile of People With Parkinson's Disease Treated With a Device-Aided Therapy in Spain. A Comparative Multicenter Observational Study.

Diego Santos-García, Ángela Solleiro, Guillermo González-Ortega, Pablo Mir, Nuria López-Ariztegui, Rocío García Ramos, Inés Legarda, Anna Planas-Ballvé, Deborah Alonso-Modino, Pilar Sánchez-Alonso and 4 more

Abstract readMulticenter StudyObservational StudyComparative Study
In one paragraph

Observational study in Movement disorders clinical practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Observational
  3. Observational
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Diego Santos-GarcíaCHUAC, Complejo Hospitalario Universitario de A Coruña, A Coruña, Spain.ORCID https://orcid.org/0000-0002-3126-5111
Ángela SolleiroGrupo de Investigación en Enfermedad de Parkinson y otros Trastornos del Movimiento, INIBIC (Instituto de Investigación Biomédica de A Coruña), A Coruña, Spain.
Guillermo González-OrtegaHospital Universitario de Móstoles, Madrid, Spain.ORCID https://orcid.org/0000-0002-4763-3265
Pablo MirUnidad de Trastornos del Movimiento, Servicio de Neurología y Neurofisiología Clínica, Instituto de Biomedicina de Sevilla, Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Seville, Spain.ORCID https://orcid.org/0000-0003-1656-302X
Nuria López-ArizteguiHospital Universitario de Toledo, Toledo, Spain.ORCID https://orcid.org/0000-0001-7172-3191
Rocío García RamosHospital Universitario Clínico San Carlos, Madrid, Spain.
Inés LegardaHospital Universitario Son Espases, Palma de Mallorca, Spain.
Anna Planas-BallvéConsorci Sanitari Integral, Hospital Moisés Broggi, Sant Joan Despí, Spain.
Deborah Alonso-ModinoHospital Universitario de la Candelaria, Santa Cruz de Tenerife, Spain.
Pilar Sánchez-AlonsoHospital Universitario Puerta de Hierro, Madrid, Spain.
Iria CaboComplejo Hospitalario Universitario de Pontevedra (CHOP), Pontevedra, Spain.
Marta Blázquez-EstradaHospital Universitario Central de Asturias (HUCA), Oviedo, Spain.
Álvaro Sánchez-FerroCIBERNED (Centro de Investigación Biomédica en Red Enfermedades Neurodegenerativas), Madrid, Spain.
DATs‐PD GETM Spanish Registry Group

Funding

Fundación Novoa Santos 25.000 euros
6 · The paper itself

Abstract

BACKGROUND AND

objectiveNew device-aided therapies (DATs) have emerged to treat people with Parkinson's disease (PwP). Our aim was to know which DATs were indicated by the neurologist and to compare the characteristics of the patients treated under real clinical practice in Spain in the year 2024. PATIENTS AND

methodsData collected in the DATs-PD GETM Spanish Registry were used (REDCap). This is a descriptive, observational, prospective, multicenter, clinical registry with progressive inclusion of PwP treated with a DAT in daily clinical practice conditions in more than 40 centers from Spain for 10 years. For this proposal, only data from visit V1 (indication of DAT) were analyzed, but no follow-up data. All patients with information on DAT received until 31/DEC/2024 were included.

resultsA total of 313 PD patients (66.7 ± 9.6 years old at V2; 61.7% males) were treated with a DAT. The most frequent DAT was subcutaneous foslevodopa/foscarbidopa (fLD/fCD) (47%) followed by deep brain stimulation (DBS) (20.1%) and continuous subcutaneous apomorphine infusion (CSAI) (19.8%). Up to 23.6% had received at least one previous DAT and 47% an on-demand therapy. Differences in age, time with fluctuations and other aspects (motor status, quality of life or activities of daily living among others) were observed between different DAT groups. Specifically, patients treated with DBS were younger and had less advanced disease, whereas those who received LECIG were the most affected.

conclusionSubcutaneous therapies and DBS were the most frequent DATs (86.9%) implemented in Spain in 2024. Profile differences were detected between DAT types.

Indexed as

Antiparkinson AgentsDeep Brain StimulationParkinson DiseaseAgedFemaleHumansMaleMiddle AgedProspective StudiesRegistriesSpainAntiparkinson Agentsdeep brain stimulationdevice‐aided therapiesinfusionParkinson's diseaseregistrysubcutaneous

Identifiers

PMID40704401
PMCPMC12839489

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.