Evidence map›Paper›PMID 40705102›Full record

ReviewClinical and experimental nephrology2025

Management of hyperkalemia: strategic clinical actions in real-world practice.

Takuya Fujimaru, Kazuhito Hirose, Masahiko Yazawa, Masahiko Nagahama, Csaba P Kovesdy, Electrolyte Winter Seminar Collaborative Group

Abstract readReview
In one paragraph

Review in Clinical and experimental nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Severe hyperkalemia and muscle weakness in HIV-associatedRespiratory medicine case reports · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Takuya FujimaruDepartment of Nephrology, St. Luke's International Hospital, 9-1 Akashi-cho, Chuo-ku, Tokyo, 104-8560, Japan. fujitaku@luke.ac.jp.ORCID http://orcid.org/0000-0002-6825-3456
Kazuhito HiroseDepartment of General Medicine, Tsukuba Medical Center Hospital, Tsukuba, Japan.
Masahiko YazawaDepartment of Internal Medicine, Yokohama General Hospital, Yokohama, Japan.
Masahiko NagahamaDepartment of Nephrology, St. Luke's International Hospital, 9-1 Akashi-cho, Chuo-ku, Tokyo, 104-8560, Japan.
Csaba P KovesdyDivision of Nephrology, Department of Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.
Electrolyte Winter Seminar Collaborative Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This article is part of a review series on water and electrolyte disorders, based on the annual "Electrolyte Winter Seminar" for early-career nephrologists in Japan. The seminar features interactive case-based discussions, some of which are included as self-assessment questions. The fifth installment addresses the management of hyperkalemia. Hyperkalemia frequently occurs in patients with chronic kidney disease (CKD) and can become life-threatening when severe, necessitating prompt treatment regardless of its underlying cause. Renin-angiotensin system inhibitors (RASi) are a recognized risk factor for hyperkalemia in CKD; however, discontinuing RASi in response to elevated potassium levels may adversely affect patient outcomes. Although there are no formal criteria distinguishing acute from chronic hyperkalemia, symptoms presentation and potassium levels offer a practical guide for clinical management. This review covers standard treatment strategies for severe (symptomatic or acute) hyperkalemia in emergency and inpatient settings and discusses how to manage mild-to-moderate (asymptomatic or chronic) cases in CKD patients while continuing RASi therapy.

Indexed as

HyperkalemiaPotassiumRenal Insufficiency, ChronicAngiotensin-Converting Enzyme InhibitorsHumansRenin-Angiotensin SystemRisk FactorsAngiotensin-Converting Enzyme InhibitorsPotassiumChronic kidney diseaseDyskalemiaHyperkalemiaPotassium

Identifiers

PMID40705102
PMCPMC12660465

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.