ReviewCurrent nutrition reports2025
Aging-Related Obesity: Unveiling Mitochondrial and Metabolic Dysfunction.
Review in Current nutrition reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Dynamic collaboration between mitochondria and organelles: mechanisms, functions, and disease implications.Apoptosis : an international journal on programmed cell death · 2026Review
- Mechanistic Modulation of Autophagy by Bioactive Natural Products: Implications for Human Aging and Longevity.Nutrients · 2026Review
- Long-term effectiveness of multidisciplinary weight management versus routine management on body mass index and waist circumference in older adults with overweight and obesity: a 24-month retrospective cohort study.BMC public health · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
purpose of reviewThis review aims to elucidate the complex relationship between aging and obesity, clarify the mechanisms underlying mitochondrial dysfunction, and highlight the critical role of obesity as a major risk factor for chronic metabolic diseases. Aging is a growing global concern, and obesity in the elderly has profound implications for health and imposes a significant long-term burden on healthcare systems. Obesity impairs mitochondrial function, increasing the risk of sarcopenic obesity and a range of chronic conditions, including diabetes, hypertension, cardiovascular disease, thyroid dysfunction, and neurodegenerative disorders. This review seeks to comprehensively assess the bidirectional relationship between aging and obesity, providing novel insights for future research. RECENT
findingsEmerging evidence suggests that obesity may accelerate the aging process, and that aging and obesity-related metabolic diseases mutually exacerbate the development of chronic conditions, leading to substantial health risks. A deeper understanding of the molecular mechanisms underlying mitochondrial and metabolic dysfunction in the context of aging and obesity is essential to clarify their adverse effects on elderly health. Furthermore, developing comprehensive preventive and therapeutic strategies targeting these conditions is critical for improving outcomes in the aging population.
Indexed as
Identifiers
40705147What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.