Evidence map›Paper›PMID 40707451›Full record

ArticleNature communications2025

A unimolecule nanopesticide delivery system applied in field scale for enhanced pest control.

Xingye Li, Xinyue Wang, Changjiao Sun, Anqi Wang, Changcheng An, Ningjun Li, Yue Shen, Jiachong Hu, Huihui Liu, Jing Xie and 2 more

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xingye LiInstitute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing, PR China.ORCID http://orcid.org/0000-0002-1598-7325
Xinyue WangInstitute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing, PR China.
Changjiao SunInstitute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing, PR China.ORCID http://orcid.org/0000-0002-8246-1526
Anqi WangInstitute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing, PR China.
Changcheng AnInstitute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing, PR China.
Ningjun LiInstitute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing, PR China.
Yue ShenInstitute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing, PR China.
Jiachong HuInstitute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing, PR China.
Huihui LiuInstitute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing, PR China.
Jing XieInstitute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing, PR China.
Dan LuoDepartment of Biological and Environmental Engineering, Kavli Institute at Cornell for Nanoscale Science, Cornell University, Ithaca, NY, USA.ORCID http://orcid.org/0000-0002-1236-4069
Yan WangInstitute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing, PR China. wangyan03@caas.cn.ORCID http://orcid.org/0000-0003-4491-7032

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanopesticides provide immense potential in reducing pesticide use and promoting sustainable agriculture for their enhanced pesticidal efficacy. Nano-enabled delivery systems can enhance pesticide penetration into both insects and leaves through their unique nanoproperties, in particular their small size. However, it remains a great challenge to achieve unimolecular formulations in water-based processes in order to take full advantages of nanoproperties. Here, using ionic liquid, we fabricate unimolecular nanopesticides (about 3 nm in average diameter) in a water-based process, termed unimolecule-nanopesticide delivery system. Guided by the density functional theory calculations, we successfully convert various traditional pesticides into the unimolecule-nanopesticide system, significantly enhancing cellular uptake, insect-dermis translocation, and leaf-cuticle penetration of pesticides. Furthermore, we improved field efficacy against multiple pests using the unimolecule-nanopesticide system. Importantly, the unimolecule-nanopesticide system utilizes only industry-grade raw materials that are Generally Recognized as Safe by the US Food and Drug Administration. We believe our unimolecule-nanopesticide system represents a water-based and facile-manufactured platform for other conventional pesticides to achieve high-efficiency field-scale plant protection.

Indexed as

Drug Delivery SystemsNanoparticlesPest ControlPesticidesAnimalsInsectaInsecticidesIonic LiquidsNanostructuresPlant LeavesInsecticidesIonic LiquidsPesticides

Identifiers

PMID40707451
PMCPMC12290072

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.