ReviewInternational journal of obesity (2005)2025
Methodological issues related to maximal fat oxidation and FATmax reproducibility: a narrative review.
Review in International journal of obesity (2005), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- V̇OScandinavian journal of medicine & science in sports · 2026Article
- The impact of maximal fat oxidation intensity exercise on glucose and lipid metabolism in individuals with overweight or obesity: A systematic review and meta-analysis.Biology of sport · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Maximal fat oxidation (MFO) and its corresponding exercise intensity (FATmax) seem to be reduced in individuals with obesity and cardio-metabolic diseases, showing a direct correlation with insulin resistance or sensitivity, muscle oxidative capacity, and adipose tissue lipolysis. In this review, we conducted a systematic search of the PubMed, Scopus, and Web of Science databases, summarizing the findings from 11 studies that evaluated the reproducibility of MFO and FATmax in both healthy individuals and people with obesity. Furthermore, we examine whether the reproducibility of these biomarkers is related to biological or methodological factors, underscoring the importance of standardizing pre-test macronutrient intake and physical activity levels. To further contribute to a standardized assessment of MFO and FATmax, this paper also discusses which exercise protocols and analytical procedures can be applied to minimize its measurement error. Finally, based on the accuracy of different gas analyzers for calculating substrate oxidation at FATmax, this review debates whether the reported day-to-day variation of these biomarkers may only represent the measurement error of these devices. Practical applications of MFO and FATmax reproducibility in the context of scientific research and exercise prescription are also provided, preventing biased hypothesis and theoretical models regarding fat oxidation capacity and cardio-metabolic health.
Indexed as
Identifiers
40707656What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.