Evidence map›Paper›PMID 40708209›Full record

ArticleThe Journal of physiology2026

Small current, big potential: bridging mechanistic insight of the SK channel with translational promise.

Yang Zheng, Miao Zhang, Nipavan Chiamvimonvat

Abstract read
In one paragraph

Article in The Journal of physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yang ZhengDepartment of Basic Medical Sciences, University of Arizona College of Medicine, Phoenix, Arizona, USA.
Miao ZhangDepartment of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharmacy, Irvine, California, USA.
Nipavan ChiamvimonvatDepartment of Basic Medical Sciences, University of Arizona College of Medicine, Phoenix, Arizona, USA.ORCID https://orcid.org/0000-0001-9499-8817

Funding

Functional Interactions of Cardiac Ion ChannelsR01HL085844 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CHIAMVIMONVAT, NIPAVAN · 2007 to 2025
$7.3M
Targeting the genotype to phenotype link in HCM as a therapeutic strategyR01HL152055 · NHLBI · STANFORD UNIVERSITY · PI MERCOLA, MARK · 2021 to 2024
$2.3M
Development of SK channel modulators as therapeutic agents for ataxiaR33NS101182 · NINDS · CHAPMAN UNIVERSITY · PI BEZPROZVANNY, ILYA B, ZHANG, MIAO · 2021 to 2021
$723k
Heart Rhythm Society (HRS)HHS | National Institutes of Health (NIH) NIH R01 HL170520HHS | National Institutes of Health (NIH) NIH R15 NS130420NHLBI NIH HHS R01 HL085844NHLBI NIH HHS R01 HL152055NINDS NIH HHS R33 NS101182
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

anti‐arrhythmic drugsatrial fibrillationproarrhythmiaSK channel inhibitorsSK (KCa2) channelssmall conductance calcium‐activated potassium channelstherapeutics

Identifiers

PMID40708209
PMCPMC13327765

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.