Evidence map›Paper›PMID 40708249›Full record

ArticleEuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology2025

Impact of intracoronary supersaturated oxygen therapy on microvascular obstruction and infarct size in patients with acute anterior myocardial infarction.

Tobias König, Dominik Berliner, Johanna Diekmann, Muharrem Akin, Tobias Pfeffer, Carolina Sanchez Martinez, Vera Garcheva, Frank M Bengel, Johann Bauersachs, Andreas Schäfer

Abstract read
In one paragraph

Article in EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Coronary Slow Flow and No-Reflow During Percutaneous Coronary Intervention: Contemporary Insights Into Imaging-Guided Prediction, Prevention, and Management.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026
    Review
  2. Supersaturated oxygen therapy to reduce myocardial infarct size: time to pay attention!EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tobias KönigDepartment of Cardiology and Angiology, Hannover Medical School, Hanover, Germany.
Dominik BerlinerDepartment of Cardiology and Angiology, Hannover Medical School, Hanover, Germany.
Johanna DiekmannDepartment of Nuclear Medicine, Hannover Medical School, Hanover, Germany.
Muharrem AkinDepartment of Cardiology and Angiology, Hannover Medical School, Hanover, Germany.
Tobias PfefferDepartment of Cardiology and Angiology, Hannover Medical School, Hanover, Germany.
Carolina Sanchez MartinezDepartment of Cardiology and Angiology, Hannover Medical School, Hanover, Germany.
Vera GarchevaDepartment of Cardiology and Angiology, Hannover Medical School, Hanover, Germany.
Frank M BengelDepartment of Nuclear Medicine, Hannover Medical School, Hanover, Germany.
Johann BauersachsDepartment of Cardiology and Angiology, Hannover Medical School, Hanover, Germany.
Andreas SchäferDepartment of Cardiology and Angiology, Hannover Medical School, Hanover, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFinal infarct size (FIS) and microvascular obstruction (MVO) are associated with heart failure hospitalisations and mortality in patients with acute myocardial infarction (AMI). Interventions beyond primary percutaneous coronary intervention (PCI) to reduce FIS are needed. Supersaturated oxygen (SSO

aimsWe aimed to investigate whether routine use of SSO

methodsIntracoronary SSO

resultsThe two groups did not significantly differ regarding sex, age, weight, hypertension, dyslipidaemia, smoking and diabetes status, prehospital cardiac arrest, door-to-balloon time, Thrombolysis in Myocardial Infarction flow before and after PCI, or renal function (p>0.1 for each) and had comparable area at risk by CMR and FAPI-PET. SSO

conclusionsSSO

Indexed as

Anterior Wall Myocardial InfarctionMyocardial InfarctionOxygenOxygen Inhalation TherapyAgedFemaleHumansMaleMicrocirculationMiddle AgedPercutaneous Coronary InterventionTomography, Emission-Computed, Single-PhotonTreatment OutcomeOxygen

Identifiers

PMID40708249
PMCPMC12285395

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.