Evidence map›Paper›PMID 40709991›Full record

ArticleDiseases (Basel, Switzerland)2025

Subcutaneous Panniculitis-like T-Cell Lymphoma: Diagnostic Challenge and Successful Multimodal Management with Integra

Daniel Pit, Teodora Hoinoiu, Bogdan Hoinoiu, Simona Cerbu, Maria Iordache, Adrian Vaduva, Diana Szilagyi, Claudia Ramona Bardan, Panche Taskov, Zorin Petrisor Crainiceanu and 2 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Diseases (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Daniel PitDoctoral School, Victor Babes University of Medicine and Pharmacy, E. Murgu Square, No. 2, 300041 Timisoara, Romania.ORCID 0009-0005-3386-8468
Teodora HoinoiuDiscipline of Clinical Practical Skills, Department I Nursing, Faculty of Medicine, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania.ORCID 0000-0001-7753-7621
Bogdan HoinoiuDepartment of Oral Rehabilitation and Dental Emergencies, Faculty of Dentistry, Victor Babes University of Medicine and Pharmacy, P-ta Eftimie Murgu 2, 300041 Timisoara, Romania.ORCID 0000-0002-5217-7655
Simona CerbuDepartment XV of Orthopaedics, Traumatology, Urology and Medical Imaging, Discipline of Radiology and Medical Imaging, Victor Babeș University of Medicine and Pharmacy, 300041 Timișoara, Romania.
Maria IordacheDepartment of Hematology, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Adrian VaduvaDepartment of Pathology, Faculty of Medicine, ANAPATMOL Research Center, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania.ORCID 0000-0001-9261-5309
Diana SzilagyiDepartment of Pathology, "Pius Brinzeu" County Clinical Emergency Hospital, 300723 Timisoara, Romania.
Claudia Ramona BardanDoctoral School, Victor Babes University of Medicine and Pharmacy, E. Murgu Square, No. 2, 300041 Timisoara, Romania.
Panche TaskovDoctoral School, Victor Babes University of Medicine and Pharmacy, E. Murgu Square, No. 2, 300041 Timisoara, Romania.
Zorin Petrisor CrainiceanuPlastic Surgery Department, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania.ORCID 0000-0002-2880-7485
Miruna SamfireagDiscipline of Clinical Practical Skills, Department I Nursing, Faculty of Medicine, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania.ORCID 0000-0001-5358-882X
Razvan BardanDepartment XV, Discipline of Urology, Victor Babes University of Medicine and Pharmacy, E. Murgu Square, No. 2, 300041 Timisoara, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesSubcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a rare and aggressive cutaneous lymphoma, often misdiagnosed due to nonspecific clinical features. Early diagnosis and treatment remain challenging.

methodsWe report the case of a 31-year-old female with a chronic non-healing gluteal wound initially treated as an abscess. The lack of improvement prompted repeated investigations, culminating in the diagnosis of SPTCL with an alpha-beta T-cell phenotype.

resultsManagement involved combined chemotherapy and surgical wound reconstruction. Six cycles of CHOEP-21 chemotherapy led to complete clinical remission. A soft tissue defect superinfected with multidrug-resistant organisms was successfully reconstructed using Integra Dermal Regeneration Template followed by split-thickness skin grafting.

conclusionsThis case highlights the diagnostic complexity of SPTCL and the therapeutic potential of dermal matrix application in complex wound management, especially in immuno-compromised patients.

Indexed as

chemotherapydermal matrixIntegra®lymphomasoft tissue defects

Identifiers

PMID40709991
PMCPMC12293277

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.