Evidence map›Paper›PMID 40711294›Full record

ArticleVeterinary sciences2025

In Vitro Antiviral Activity of the Fungal Metabolite 6-Pentyl-α-Pyrone Against Bovine Coronavirus: A Translational Study to SARS-CoV-2.

Violetta Iris Vasinioti, Amienwanlen Eugene Odigie, Maria Stella Lucente, Luca Del Sorbo, Cristiana Catella, Elisabetta Casalino, Maria Michela Salvatore, Alessia Staropoli, Francesco Vinale, Maria Tempesta and 5 more

Abstract read
In one paragraph

Article in Veterinary sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Violetta Iris VasiniotiDepartment of Veterinary Medicine, University of Bari, 70010 Valenzano, Italy.ORCID 0000-0002-3798-0407
Amienwanlen Eugene OdigieDepartment of Veterinary Medicine, University of Bari, 70010 Valenzano, Italy.ORCID 0000-0002-8546-2997
Maria Stella LucenteDepartment of Veterinary Medicine, University of Bari, 70010 Valenzano, Italy.
Luca Del SorboDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, 80137 Naples, Italy.
Cristiana CatellaDepartment of Veterinary Medicine, University of Bari, 70010 Valenzano, Italy.ORCID 0000-0002-9594-5255
Elisabetta CasalinoDepartment of Veterinary Medicine, University of Bari, 70010 Valenzano, Italy.ORCID 0000-0001-9330-350X
Maria Michela SalvatoreDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, 80137 Naples, Italy.ORCID 0000-0001-8318-3065
Alessia StaropoliDepartment of Agricultural Sciences, University of Naples Federico II, 80055 Portici, Italy.ORCID 0000-0002-8946-1609
Francesco VinaleDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, 80137 Naples, Italy.ORCID 0000-0002-5090-8127
Maria TempestaDepartment of Veterinary Medicine, University of Bari, 70010 Valenzano, Italy.ORCID 0000-0003-4300-8822
Filomena FioritoDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, 80137 Naples, Italy.ORCID 0000-0002-6658-7807
Anna AndolfiDepartment of Chemical Science, University of Naples Federico II, 80126 Naples, Italy.ORCID 0000-0001-8949-3654
Alessio BuonavogliaDental School, Department of Biomedical and Neuromotor Sciences, University of Bologna, 40126 Bologna, Italy.ORCID 0000-0002-1044-2027
Annamaria PratelliDepartment of Veterinary Medicine, University of Bari, 70010 Valenzano, Italy.ORCID 0000-0001-6862-1792
Paolo CapozzaDepartment of Veterinary Medicine, University of Bari, 70010 Valenzano, Italy.ORCID 0000-0001-5563-1131

Funding

European Union-Next Generation EU Project PRIN Prot. 2022WTWB9R
6 · The paper itself

Abstract

The recent COVID-19 pandemic has prompted the scientific community to prioritize the discovery of preventive methods and new therapeutics, including the investigation of natural compounds with antiviral potential. Fungal secondary metabolites (SMs) represent a promising source of antiviral drugs due to their structural diversity and intrinsic biocompatibility. Herein, the antiviral activity of 6-pentyl-α-pyrone (6PP) against bovine coronavirus (BCoV) has been evaluated in vitro. Considering that BCoV and SARS-CoV-2 are both members of the

Indexed as

6-pentyl-α-pyroneantiviral activityBCoVCOVID-19

Identifiers

PMID40711294
PMCPMC12298981

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.