ArticleObesity surgery2025
Evaluating Weight Loss Associated with Bariatric Surgery After Liraglutide Use: A Matched Population-Level Retrospective Cohort Study.
Article in Obesity surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Treating Severe Obesity: A Medical Perspective.Advances in therapy · 2026Review
- Prescriptions for Glucagon-Like Peptide 1 Agonists (GLP-1RAs) Before Bariatric Surgery in the US.Annals of surgery · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionGlucagon-like peptide 1 (GLP-1) analogues are an emerging class of medications used to treat obesity. While studies show that postoperative liraglutide use is an effective adjunct treatment for patients with unsuccessful weight loss after bariatric surgery, the impact of preoperative liraglutide use on postoperative outcomes remains poorly understood. Therefore, the aim of this study was to determine if postoperative weight loss and comorbidity outcomes differ for patients who use liraglutide before their bariatric surgery.
methodsUsing data from the Ontario Bariatric Registry (OBR), we conducted a retrospective, matched cohort study of patients who underwent a primary bariatric procedure between January 2010 and June 2020. Liraglutide naive patients were matched with preoperative liraglutide users. The primary outcome of interest was percentage total body weight lost (TWL) from baseline to 1-year post-surgery.
resultsA total of 1383 liraglutide naive patients were successfully matched to 449 liraglutide users at a ratio of 3:1. 1-year post-surgery; there were differences observed between groups in the primary outcome examined, with a higher TWL observed in the liraglutide naive group (27.52 ± 10.28% liraglutide naive vs. 25.46 ± 9.04% liraglutide users, p < 0.001).
conclusionsWhile an increase in weight loss was observed in liraglutide naive patients, both groups had clinically significant weight loss and similar BMIs at 1-year post-surgery. This suggests that preoperative GLP-1 analogue users and GLP-1 analogue naive patients both benefit substantially from bariatric surgery.
Indexed as
Identifiers
40711700What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.