Evidence map›Paper›PMID 40711887›Full record

ArticleJournal of diabetes investigation2025

A multicenter, prospective, real-world study of oral semaglutide in adults with type 2 diabetes in Japanese clinical practice (PIONEER REAL Japan): Subgroup analyses.

Daisuke Yabe, Yoshiyuki Hamamoto, Daiji Kawanami, Rimei Nishimura, Yasuo Terauchi, Hanan Amadid, Uffe Christian Braae, Atheline Major-Pedersen, Ryo Suzuki

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of diabetes investigation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Daisuke YabeDepartment of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Kyoto, Japan.ORCID https://orcid.org/0000-0002-5334-7687
Yoshiyuki HamamotoYutaka Seino Distinguished Center for Diabetes Research, Kansai Electric Power Medical Research Institute, Kyoto, Japan.ORCID https://orcid.org/0000-0002-1938-7394
Daiji KawanamiDepartment of Endocrinology and Diabetes, Fukuoka University School of Medicine, Fukuoka, Japan.ORCID https://orcid.org/0000-0002-8926-4701
Rimei NishimuraDivision of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, Japan.
Yasuo TerauchiDepartment of Endocrinology and Metabolism, Graduate School of Medicine, Yokohama City University, Yokohama, Japan.
Hanan AmadidClinical Development and Project Leadership, Novo Nordisk A/S, Søborg, Denmark.
Uffe Christian BraaeReal-World Science, Novo Nordisk A/S, Søborg, Denmark.
Atheline Major-PedersenGlobal Patient Safety, Novo Nordisk A/S, Søborg, Denmark.
Ryo SuzukiDepartment of Diabetes, Metabolism and Endocrinology, Tokyo Medical University, Tokyo, Japan.ORCID https://orcid.org/0000-0002-2965-6906

Funding

Novo Nordisk A/S
6 · The paper itself

Abstract

aimsHbA

methodsIn this non-interventional study, changes in HbA

resultsAll subgroups experienced reductions in HbA

conclusionsHbA

Indexed as

BiomarkersDiabetes Mellitus, Type 2Glucagon-Like PeptidesHypoglycemic AgentsAdministration, OralAdultAgedBlood GlucoseBody WeightEast Asian PeopleFemaleFollow-Up StudiesGlucagon-Like Peptide 1Glycated HemoglobinHumansJapanBiomarkersBlood GlucoseGlucagon-Like Peptide 1Glucagon-Like PeptidesGlycated Hemoglobinhemoglobin A1c protein, humanHypoglycemic AgentsSemaglutideOral semaglutideReal‐world studyType 2 diabetes

Identifiers

PMID40711887
PMCPMC12489328

What Socratic holds

Texttitle and abstract
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.