Evidence map›Paper›PMID 40715058›Full record

ReviewNature communications2025

Opportunities and challenges with the implementation of normothermic machine perfusion in kidney transplantation.

Ton J Rabelink, Sarah Hosgood, Thomas Minor, Markus Selzner, Annemarie Weissenbacher, Henri Gd Leuvenink, Stefan Schneeberger

Abstract readReview
In one paragraph

Review in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. CRISPR-based ex vivo gene editing of donor organs.Nature reviews bioengineering · 2026
    Article
  3. Revealing the potential of non-transplanted donor organs: a comparative analysis in the Eurotransplant region.Transplant international : official journal of the European Society for Organ Transplantation · 2026
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ton J RabelinkDepartment of Medicine and Transplant Center, Leiden University Medical Center, Leiden, The Netherlands.ORCID http://orcid.org/0000-0001-6780-5186
Sarah HosgoodDepartment of Surgery, University of Cambridge. Addenbrooke's Hospital. Level 9. CB2 0QQ, Cambridge, UK.
Thomas MinorSurgical Research Dpt. Clinic of General, Visceral and Transplant Surgery, University Hospital Essen, Hufelandstr. 55, 45147, Essen, Germany.ORCID http://orcid.org/0000-0002-7124-3590
Markus SelznerUniversity Health Network Toronto - MaRS Building, 585 University Avenue, Toronto, ON, M5G2N2, Canada.ORCID http://orcid.org/0000-0002-4326-0887
Annemarie WeissenbacherDept. of Visceral, Transplant and Thoracic Surgery, organLife Lab, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.ORCID http://orcid.org/0000-0002-0582-1815
Henri Gd LeuveninkComprehensive Transplant Center, University of Groningen, Hanzeplein 1, 9713GZ, Groningen, The Netherlands.
Stefan SchneebergerDept. of Visceral, Transplant and Thoracic Surgery, organLife Lab, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria. stefan.schneeberger@i-med.ac.at.ORCID http://orcid.org/0000-0002-2619-8639

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

End stage kidney disease and dialysis are lifetime limiting and lifestyle-defining conditions with enormous costs to the health care system. Despite a severe organ shortage, thousands of organs that are retrieved for transplantation go to waste every year because of the presumed inadequacy of organ quality and/or the limited organ preservation time. Normothermic kidney machine perfusion (NMP) holds the potential to resolve this through improved preservation, prolonged preservation time, kidney quality assessment, reconditioning and treatment. We herein develop a perspective on the potential, but also the hurdles towards the breakthrough of this technology.

Indexed as

Kidney TransplantationOrgan PreservationPerfusionAnimalsHumansKidneyKidney Failure, Chronic

Identifiers

PMID40715058
PMCPMC12296735

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.