ArticleNature communications2025
Arbovirus suppression of a lectin protein-mediated broad-spectrum resistance enhances herbivorous vector performance and viral transmission.
Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
4 citing papers in PubMed.
- A plant virus-derived siRNA modulates wing dimorphism and fertility of vector insects to enhance virus spread.Journal of advanced research · 2026Article
- Active but not passive passengers: Persistent-propagative plant viruses manipulate insect vectors for efficient transmission.PLoS pathogens · 2026Review
- From triangle to pyramid: Understanding host-pathogen-microniome-environment interplay for sustainable, enviromics-empowered management of plant diseases.Plant communications · 2026Review
- Diverse RNA viral effectors converge on facilitation of AGO4 degradation to promote infection.Nucleic acids research · 2025Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Arboviruses often employ various strategies to manipulate the behavior of herbivorous vectors and host plants, thereby enhancing their transmission and infection. In this study, we identify a plant lectin protein, OsChtBL1, which possesses chitin-binding activity and specifically accumulates on the stylets of insect vectors. This binding creates a feeding barrier that reduces the vectors' efficiency in acquiring and transmitting the virus. However, the rice stripe virus, a devastating pathogen in rice, counteracts this defense by utilizing a viral protein to recruit an E3 ubiquitin ligase, leading to the degradation of OsChtBL1. This degradation facilitates vector feeding and enhances viral transmission. Our findings provide insights into how arbovirus-infected host plants improve the performance of herbivorous vectors and offer deeper understanding of the complex interactions among arboviruses, vectors, and host plants.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.