Evidence map›Paper›PMID 40715145›Full record

ArticleNature communications2025

Spatiotemporal H

Maurice O'Mara, Suisheng Zhang, Ulla G Knaus

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Review
  3. Modulating Calcium Homeostasis via a Biomimetic Scaffold to Rescue Diabetic Ischemic Wounds.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  4. Catalase-like activity of CoMikrochimica acta · 2026
    Article
  5. Review
  6. Article
  7. The Fer Tyrosine Kinase Mediates EGFR Activation in Sperm Capacitation.International journal of molecular sciences · 2025
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Maurice O'MaraConway Institute, School of Medicine, University College Dublin, Dublin, Ireland.
Suisheng ZhangConway Institute, School of Medicine, University College Dublin, Dublin, Ireland.
Ulla G KnausConway Institute, School of Medicine, University College Dublin, Dublin, Ireland. ulla.knaus@ucd.ie.ORCID http://orcid.org/0000-0002-7375-0385

Funding

Irish Research Council for Science, Engineering and Technology (IRCSET) GOIPG/2019/55Science Foundation Ireland (SFI) 16/IA/4501Science Foundation Ireland (SFI) 22/FFP-A/10349
6 · The paper itself

Abstract

Well-organized repair of damaged barrier epithelia is vital for infection control, resolution of inflammation, and enduring physical protection. Cysteine thiol and methionine oxidation are connected to cytoskeletal rearrangements in cell migration and wound healing, but how localized redox signaling is achieved to regulate dynamic processes remains elusive. Here, we identify DUOX2, a mucosal barrier NADPH oxidase, as vesicle-incorporated H

Indexed as

Actin CytoskeletonCell MovementHydrogen PeroxideWound HealingActinsAnimalsDual OxidasesEpithelial CellsHumansMicePseudopodiaSignal TransductionActinsDual OxidasesDUOX2 protein, humanHydrogen Peroxide

Identifiers

PMID40715145
PMCPMC12297405

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.