ReviewNature reviews. Microbiology2025
Microbial metal physiology: ions to ecosystems.
Review in Nature reviews. Microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- The Role of Porin Proteins and ygiU-nhaR in the Formation of Biofilm in Escherichia coli.Current microbiology · 2026Article
- The iron paradox and particle size sensing: transcriptomic response ofApplied and environmental microbiology · 2026Article
- Targeting Ferroptosis and Cuproptosis for Antimicrobial Control in Postharvest Preservation.Comprehensive reviews in food science and food safety · 2026Review
- Cobalt and nickel ion synergy promotes gene amplification and stable metal resistance inApplied and environmental microbiology · 2026Article
- Silver-based N-heterocyclic carbene (NHC) complexes as emerging strategies against antimicrobial resistance.Archives of microbiology · 2026Review
- Contrasts and similarities in the transcriptomic response to antimicrobial coinage metals inMicrobiology spectrum · 2026Article
- Seasonal Trade-Offs Between Sedimentary Bacterial Generalists and Specialists Sustain Community Stability in Rivers.Environmental microbiology · 2026Article
- Transporter promiscuity and redox-driven metal partitioning in plant responses to chemically analogous metals.Plant cell reports · 2026Review
- Sex bias in iron sequestration by transferrin 1 modulates sexually dimorphic infection outcomes in Drosophila melanogaster.Genetics · 2026Article
- Article
- Deletion ofApplied and environmental microbiology · 2026Article
- Combating Bacterial Infection with Metabolism-Regulating Nanomaterials.International journal of nanomedicine · 2026Review
- CrpH ofFrontiers in microbiology · 2026Article
- A flow equilibrium model controlling cytoplasmic transition metal cation pools and preventing mis-metalation as exemplified for zinc homeostasis.Journal of bacteriology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Life depends on metal ions. The levels of metal ions vary widely across environments; many areas of the open ocean are chronically metal-limited, whereas other natural and human-affected environments have exceptionally high metal concentrations. Within the human host, the fitness of commensal and pathogenic microorganisms can be constrained by both metal limitation and intoxication. Limitation occurs when metals are deficient or in forms not suitable for import. Conversely, metal excess can lead to toxicity; microorganisms then rely on metal export to maintain suitable intracellular levels. Metalloregulatory systems play a central part in enabling microorganisms to acclimate to changes in metal availability. The analysis of metalloregulators and their regulons unveils physiologically relevant transport and trafficking functions, reveals processes affected by metal imbalance and provides insights into intracellular metal pools. In this Review, I explore the key processes of metal transport, trafficking, storage and regulation. I next highlight selected microorganisms that illustrate how to thrive in environments that are chronically or transiently metal-limited, or where high metal levels are toxic. A detailed understanding of microbial metal physiology can be harnessed to improve the health of diverse ecosystems, for bioremediation and biomining, and to restrict the growth of bacterial pathogens.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.