Evidence map›Paper›PMID 40715906›Full record

ReviewBiodegradation2025

Comprehensive heavy metal remediation mechanisms with insights into CRISPR-Cas9 and biochar innovations.

Akansha Garg, Prerna Chauhan, Charanjeet Kaur, Pankaj Kumar Arora, Sanjay Kumar Garg, Vijay Pal Singh, Krishna Pal Singh, Alok Srivastava

Abstract readReview
PubMed Publisher
In one paragraph

Review in Biodegradation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Toxics · 2026
    Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Akansha Garg *Department of Plant Science, MJP Rohilkhand University, Bareilly, 243006, India.
Prerna Chauhan *Department of Plant Science, MJP Rohilkhand University, Bareilly, 243006, India.
Charanjeet KaurDepartment of Microbiology, MJP Rohilkhand University, Bareilly, 243006, India.
Pankaj Kumar AroraDepartment of Plant Science, MJP Rohilkhand University, Bareilly, 243006, India.
Sanjay Kumar GargDepartment of Plant Science, MJP Rohilkhand University, Bareilly, 243006, India.
Vijay Pal SinghDepartment of Plant Science, MJP Rohilkhand University, Bareilly, 243006, India.
Krishna Pal SinghMJP Rohilkhand University, Bareilly, 243006, India.
Alok SrivastavaDepartment of Plant Science, MJP Rohilkhand University, Bareilly, 243006, India. alokplantscience@gmail.com.

Funding

DST-INSPIRE INDIA DST/INSPIRE/03/2021/002510
6 · The paper itself

Abstract

Heavy metal contamination of the environment is a serious issue, and more efficient and effective bioremediation techniques are needed. This review introduces current heavy metal bioremediation techniques, with focus on phytoremediation and microbial remediation, and recent developments in biochar and CRISPR-Cas9 technology. Phytoremediation employs the natural process of plants to accumulate and detoxify metals as an eco-friendly and sustainable technique. Microbial remediation by fungi and bacteria provides an additional approach through reduction, sequestration, and transformation of metals. Biochar as a high-carbon value-added pyrolytic biomass product improves soil quality, increases microbial activity, and adsorbs heavy metals, making bioremediation more effective. The discovery of CRISPR-Cas9 revolutionized gene engineering by allowing gene editing of plants and microbes to improve their metal tolerance and degradation. This review outlines recent developments, synergistic uses of biochar and CRISPR-Cas9, and how they might enhance phytoremediation and microbial remediation. By combining such novel technologies, strong, sustainable, and scalable solutions could be built for curbing heavy metal pollution and safeguarding environmental health.

Indexed as

CharcoalCRISPR-Cas SystemsMetals, HeavySoil PollutantsBacteriaBiodegradation, EnvironmentalGene EditingPlantsbiocharCharcoalMetals, HeavySoil PollutantsBiocharCRISPR-Cas9DetoxificationMicrobial remediationPhytoremediation

Identifiers

PMID40715906

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.