SynthesisLasers in medical science2025
Photodynamic therapy for the treatment of grade B periodontitis: a systematic review of randomized controlled trials.
Synthesis in Lasers in medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Comparative Efficacy of Thermal Ablation and Surgical Resection in Patients with Colorectal Cancer Liver Metastasis: A Systematic Review and Meta-analysis.Journal of gastrointestinal cancer · 2025Pooled it
- Indocyanine green doped with chitosan nanoparticles based antimicrobial photodynamic therapy in periodontitis patients: A randomized clinical trial.World journal of experimental medicine · 2026Trial
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThis systematic review evaluates the efficacy of photodynamic therapy (PDT) compared to conventional treatments in Grade B periodontitis.
methodsA comprehensive electronic search was conducted across PubMed, Google Scholar, Dimensions, Ebase, X-mole, and Semantic Scholar, following the PRISMA guidelines. Only randomized controlled trials (RCTs) comparing PDT with conventional periodontal treatments were included. Primary clinical outcomes included probing pocket depth (PPD), clinical attachment loss (CAL), and bleeding on probing (BOP).
resultsData from 26 RCTs involving 753 patients were analyzed, with PDT applied in 219 patients (130 males, 109 females) and conventional treatment in 314 patients (173 males, 141 females). PDT significantly reduced PPD (2.6-5.23 mm) and CAL (1.26-6.00 mm), showing comparable or superior outcomes to scaling and root planing (SRP) in several RCTs. Despite these promising results, heterogeneity in photosensitizer type, laser wavelength (660-810 nm), energy dose, and PDT session protocols contributed to variability in outcomes.
conclusionPDT demonstrates significant clinical benefits in Grade B periodontitis treatment, particularly in PPD reduction, CAL improvement, and BOP control. However, variability in treatment protocols and limited long-term follow-up data (median: 6 months) highlight the need for standardized guidelines and further high-quality RCTs.
Indexed as
Identifiers
40715926What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.