Evidence map›Paper›PMID 40717567›Full record

ArticleGut microbes2025

Interplay of miR-243 and microbial interactions in aging and transgenerational immunity.

Arun Kumar, Dilawar A Mir, Mojibur R Khan

Abstract read
In one paragraph

Article in Gut microbes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Frontiers in microbiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Arun KumarMolecular Biology and Microbial Biotechnology Laboratory, Division of Life Sciences, Institute of Advanced Study in Science and Technology (IASST), Guwahati, India.ORCID 0009-0003-9062-5695
Dilawar A MirSchool of Gerontology, University of Southern California, Los Angeles, CA, USA.ORCID 0000-0002-4758-3093
Mojibur R KhanMolecular Biology and Microbial Biotechnology Laboratory, Division of Life Sciences, Institute of Advanced Study in Science and Technology (IASST), Guwahati, India.ORCID 0000-0002-6909-1479

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNAs (miRNAs) function in post-transcriptional regulation of gene expression and influence numerous biological processes. This commentary and view provide integrated insights from Kumar et al. (2024) and Gabaldon et al. (2020), emphasizing the role of miR-243 in promoting longevity and stress adaptation in response to microbial cues. However, further research is necessary to identify precise molecular targets of miR-243, comprehend its interactions with other miRNAs, validate its conservation in higher organisms, and to explore its potential toward targeted therapeutic strategies against aging and stress-related diseases.

Indexed as

AgingMicrobial InteractionsMicroRNAsAnimalsGene Expression RegulationHumansLongevityMicroRNAsautophagy-lysosome pathwayDAF-16gut microbiotamicroRNAmiR-243proteostasistransgenerational immunity

Identifiers

PMID40717567
PMCPMC12309530

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.