Evidence map›Paper›PMID 40718354›Full record

ReviewOsteoporosis and sarcopenia2025

Bone-muscle interactions.

Hiroshi Kaji

Abstract readReview
In one paragraph

Review in Osteoporosis and sarcopenia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Associations between muscle mass and strength and bone microarchitecture in Caucasian postmenopausal women.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
    Article
  6. Physical Activity, Exerkines, and Their Role in Cancer Cachexia.International journal of molecular sciences · 2025
    Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Hiroshi KajiDepartment of Physiology and Regenerative Medicine, Kindai University Faculty of Medicine, Osaka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone and skeletal muscle jointly govern motor function, working in coordination as anatomically adjacent organs, and collaborate with through mechanical interactions. Bone and muscle cells are both derived from common mesenchymal stem cells. Muscle tissues reportedly support fracture healing and bone repair. Common factors affect muscle and bone simultaneously, and sarcopenia and osteoporosis are complications of various diseases. Research on bone-muscle interactions has progressed in the past 15 years, and clinical evidence has confirmed that a relationship exists between sarcopenia and osteoporosis. Numerous myokines or osteokines play a role in bone-muscle interactions, and the involvement of extracellular vesicles has also been suggested. Research on bone-muscle interactions may translate into clinical applications for the treatment of sarcopenia and osteoporosis.

Indexed as

BoneMuscleMyokineOsteokineSarcopenia

Identifiers

PMID40718354
PMCPMC12288928

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.