Evidence map›Paper›PMID 40719075›Full record

ReviewChemical reviews2025

Structural Engineering of Layered Nanomaterials for Biomedical Applications.

Tingting Hu, Yu Yang, Tao Wang, Min Ge, Chaojie Yu, Jiajia Zha, Xiangrong Pan, Zhan Zhou, Lufang Ma, Ruizheng Liang and 1 more

Abstract readReview
In one paragraph

Review in Chemical reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Sulfur Vacancy-Enriched CuAngewandte Chemie (International ed. in English) · 2026
    Article
  2. Sulfur Vacancy-Rich MoSAdvanced healthcare materials · 2026
    Article
  3. Review
  4. Article
  5. Article
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  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Tingting HuDepartment of Electrical Engineering, City University of Hong Kong, 83 Tat Chee Ave, Kowloon Tong, Hong Kong SAR 999077, P. R. China.
Yu YangState Key Laboratory of Chemical Resource Engineering, Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing University of Chemical Technology, Beijing 100029, P. R. China.
Tao WangState Key Laboratory of Chemical Resource Engineering, Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing University of Chemical Technology, Beijing 100029, P. R. China.
Min GeDepartment of Electrical Engineering, City University of Hong Kong, 83 Tat Chee Ave, Kowloon Tong, Hong Kong SAR 999077, P. R. China.ORCID 0000-0001-6106-2721
Chaojie YuDepartment of Electrical Engineering, City University of Hong Kong, 83 Tat Chee Ave, Kowloon Tong, Hong Kong SAR 999077, P. R. China.
Jiajia ZhaDepartment of Electrical Engineering, City University of Hong Kong, 83 Tat Chee Ave, Kowloon Tong, Hong Kong SAR 999077, P. R. China.
Xiangrong PanCollege of Chemistry and Chemical Engineering, Henan Key Laboratory of Function-Oriented Porous Materials, Luoyang Normal University, Luoyang 471934, P. R. China.
Zhan ZhouCollege of Chemistry and Chemical Engineering, Henan Key Laboratory of Function-Oriented Porous Materials, Luoyang Normal University, Luoyang 471934, P. R. China.
Lufang MaCollege of Chemistry and Chemical Engineering, Henan Key Laboratory of Function-Oriented Porous Materials, Luoyang Normal University, Luoyang 471934, P. R. China.ORCID 0000-0002-5601-6437
Ruizheng LiangState Key Laboratory of Chemical Resource Engineering, Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing University of Chemical Technology, Beijing 100029, P. R. China.ORCID 0000-0002-3930-9625
Chaoliang TanDepartment of Electrical Engineering, City University of Hong Kong, 83 Tat Chee Ave, Kowloon Tong, Hong Kong SAR 999077, P. R. China.ORCID 0000-0003-1695-5285

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Layered nanomaterials have been recognized as promising nanomaterials for biomedical applications due to their tunable crystal phase, easy exfoliation, capability as the host to be intercalated with guest species, and layer-dependent electronic/optoelectronic properties. Recent advances in structural engineering strategies enable manipulating layered nanomaterials at the atomic level, activating and/or optimizing their properties, and overcoming existing limitations for unlocking unprecedented performance in biomedical applications. In this Review, we comprehensively summarize the latest advancements in structural engineering of layered nanomaterials, focusing on their applications in the biomedical field. First, layered nanomaterials explored in the biomedical field enabled by structural engineering are presented based on their composition and structures, followed by highlighting their unique advantages for structural engineering at the atomic level. Then, the structural engineering strategies of layered nanomaterials including crystal phase engineering, defect engineering, heteroatom doping, interlayer engineering, and crystalline-to-amorphous phase engineering are comprehensively discussed, alongside insights on the advanced characterization techniques. Moreover, the transformative potential of structural engineering to optimize the performance of layered nanomaterials for diverse biomedical applications is discussed in depth. Finally, this Review is concluded with perspectives on the key challenges and bottlenecks of structural engineering of layered nanomaterials in the biomedical field, providing potential solutions and outlining future directions.

Indexed as

NanostructuresAnimalsBiocompatible MaterialsHumansBiocompatible Materials

Identifiers

PMID40719075
PMCPMC12755203

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.