Evidence map›Paper›PMID 40719193›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

Parasubthalamic Glutamatergic Neurons Coordinate Cardiovascular Homeostasis and Locomotion in Mice.

Ming-Xuan Lu, Jin-Yin Huang, Xing-Zhe Xu, Ji-Yu Sun, Dan-Ni Zou, Jia-Yao Zhang, Chen Chi, Qi Zhang, Wei-Cai Liu

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ming-Xuan LuShanghai Engineering Research Center of Tooth Restoration and Regeneration & Tongji Research Institute of Stomatology and Department of Prosthodontics & Stomatological Hospital and Dental School & Tongji University, 3663 Zhongshan North Road, Shanghai, 200072, China.
Jin-Yin HuangShanghai Engineering Research Center of Tooth Restoration and Regeneration & Tongji Research Institute of Stomatology and Department of Prosthodontics & Stomatological Hospital and Dental School & Tongji University, 3663 Zhongshan North Road, Shanghai, 200072, China.
Xing-Zhe XuShanghai Key Laboratory of Brain Functional Genomics (Ministry of Education) & Affiliated Mental Health Center (ECNU) & School of Psychology and Cognitive Science & East China Normal University, Shanghai, 200062, China.
Ji-Yu SunShanghai Engineering Research Center of Tooth Restoration and Regeneration & Tongji Research Institute of Stomatology and Department of Prosthodontics & Stomatological Hospital and Dental School & Tongji University, 3663 Zhongshan North Road, Shanghai, 200072, China.
Dan-Ni ZouShanghai Engineering Research Center of Tooth Restoration and Regeneration & Tongji Research Institute of Stomatology and Department of Prosthodontics & Stomatological Hospital and Dental School & Tongji University, 3663 Zhongshan North Road, Shanghai, 200072, China.
Jia-Yao ZhangShanghai Engineering Research Center of Tooth Restoration and Regeneration & Tongji Research Institute of Stomatology and Department of Prosthodontics & Stomatological Hospital and Dental School & Tongji University, 3663 Zhongshan North Road, Shanghai, 200072, China.
Chen ChiDepartment of Cardiology & Shanghai Chest Hospital & School of Medicine & Shanghai Jiao Tong University, Shanghai, 200030, China.
Qi ZhangShanghai Key Laboratory of Brain Functional Genomics (Ministry of Education) & Affiliated Mental Health Center (ECNU) & School of Psychology and Cognitive Science & East China Normal University, Shanghai, 200062, China.
Wei-Cai LiuShanghai Engineering Research Center of Tooth Restoration and Regeneration & Tongji Research Institute of Stomatology and Department of Prosthodontics & Stomatological Hospital and Dental School & Tongji University, 3663 Zhongshan North Road, Shanghai, 200072, China.ORCID https://orcid.org/0000-0002-7709-6771

Funding

National Natural Science Foundation of China 8227032547STI2030-Major Projects 2022ZD0205500
6 · The paper itself

Abstract

Cardiovascular homeostasis and locomotion are vital for animal survival and the maintenance of essential physiological functions. The parasubthalamic nucleus (PSTN) has recently emerged as a novel interoceptive center in the central nervous system, yet its role in coordinating cardiovascular homeostasis and locomotor behavior remains poorly understood. Here, we demonstrate that PSTN

Indexed as

HomeostasisLocomotionNeuronsAnimalsBaroreflexBlood PressureGlutamic AcidHeart RateHypertensionMaleMiceMice, Inbred C57BLSolitary NucleusGlutamic Acidcardiovascular homeostasislocomotionneural circuitsparasubthalamic nucleus

Identifiers

PMID40719193
PMCPMC12561448

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.