Evidence map›Paper›PMID 40719822›Full record

ReviewInflammopharmacology2025

Neuroprotective effects of rutin in ischemic stroke: a review.

Ali Mohammad Pourbagher-Shahri, Fatemeh Forouzanfar, Ehsan Saburi, Hanie Mahaki

Abstract readReview
PubMed Publisher
In one paragraph

Review in Inflammopharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ali Mohammad Pourbagher-ShahriNeuroscience Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Fatemeh ForouzanfarNeuroscience Research Center, Mashhad University of Medical Sciences, Mashhad, Iran. forouzanfarff@gmail.com.ORCID http://orcid.org/0000-0003-0023-6470
Ehsan SaburiMedical Genetics Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Hanie MahakiVascular and Endovascular Surgery Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ischemic stroke is among the leading causes of death and long-term disability worldwide. Significant advancements in anti-ischemic therapy have been developed in the last few decades. Nonetheless, ischemic stroke continues to pose a significant problem, with candidate medications typically failing to provide favorable clinical outcomes throughout preclinical phase testing. Rutin, a natural flavonoid, has shown preventive properties against ischemic stroke through several mechanisms, such as antioxidant, anti-apoptotic, neuroprotective, and anti-neuroinflammatory. However, further research is required to understand how rutin protects against stroke. In addition, studies on the reports on human subjects ought to be carried out.

Indexed as

Brain IschemiaIschemic StrokeNeuroprotective AgentsRutinAnimalsAntioxidantsApoptosisHumansAntioxidantsNeuroprotective AgentsRutinAntioxidantFlavonoidHerbal medicineIschemic strokeNeurological disorderRutin

Identifiers

PMID40719822

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.