Evidence map›Paper›PMID 40720229›Full record

ArticleJournal of neurophysiology2025

Impact of upper cervical spinal cord hemisection on diaphragm neuromotor control.

Obaid U Khurram, Maximilian J Kantor-Gerber, Carlos B Mantilla, Gary C Sieck

Abstract read
In one paragraph

Article in Journal of neurophysiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Obaid U KhurramDepartment of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, United States.
Maximilian J Kantor-GerberDepartment of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, United States.
Carlos B MantillaDepartment of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, United States.ORCID 0000-0001-5446-9208
Gary C SieckDepartment of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, United States.ORCID 0000-0003-3040-9424

Funding

Enhancing Respiratory Motor Function after Spinal Cord InjuryR01HL146114 · NHLBI · MAYO CLINIC ROCHESTER · PI Carlos B Mantilla, Gary C. Sieck · 2019 to 2026
$5.4M
HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01HL146114NHLBI NIH HHS R01 HL146114
6 · The paper itself

Abstract

Neural drive to the diaphragm muscle (DIAm) for breathing is generated in the medulla and descends primarily ipsilaterally to phrenic motor neurons (PhMNs) in the cervical spinal cord. Neuromotor control of the DIAm during breathing involves motor unit (MU) recruitment, sustained activity, and derecruitment, which may be differentially altered on ipsilateral and contralateral sides after C

Indexed as

Cervical CordDiaphragmMotor NeuronsRecruitment, NeurophysiologicalSpinal Cord InjuriesAnimalsElectromyographyFunctional LateralityMalePhrenic NerveRatsRats, Sprague-DawleydiaphragmEMGneuromotor controlspinal cord injurystationarity

Identifiers

PMID40720229
PMCPMC12376190

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.