Evidence mapPaperPMID 40720693Full record

ArticleNeurogastroenterology and motility2025

Distinct Subgroups in Gastroparesis Defined by Simultaneous Body Surface Gastric Mapping and Gastric Emptying Breath Testing.

Chris Varghese, I-Hsuan Huang, Gabriel Schamberg, Stefan Calder, Christopher N Andrews, Greg O'Grady, Jan Tack, Armen A Gharibans

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Article in Neurogastroenterology and motility, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

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0cells of the map it votes in
5citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Chris VargheseDepartment of Surgery, The University of Auckland, Auckland, New Zealand.ORCID https://orcid.org/0000-0001-7369-8639
I-Hsuan HuangDepartment of Gastroenterology, University Hospitals, Leuven, Belgium.
Gabriel SchambergAlimetry Ltd, Auckland, New Zealand.ORCID https://orcid.org/0000-0002-4188-9614
Stefan CalderAlimetry Ltd, Auckland, New Zealand.
Christopher N AndrewsDepartment of Gastroenterology, University of Calgary, Calgary, Canada.
Greg O'GradyDepartment of Surgery, The University of Auckland, Auckland, New Zealand.ORCID https://orcid.org/0000-0002-5998-1080
Jan TackDepartment of Gastroenterology, University Hospitals, Leuven, Belgium.
Armen A GharibansDepartment of Surgery, The University of Auckland, Auckland, New Zealand.ORCID https://orcid.org/0000-0002-9139-4740

Funding

Health Research Council of New ZealandNew Zealand Society of Gastroenterology
6 · The paper itself

Abstract

backgroundGastroparesis is a heterogeneous disorder with several contributing pathophysiologies. In this study, we used simultaneous body surface gastric mapping (BSGM) and gastric emptying breath testing (GEBT) to subgroup patients with gastroparesis based on dynamic spectral meal response profiles and emptying rate.

methodsPatients with chronic gastroduodenal symptoms and negative gastroscopy underwent simultaneous BSGM and GEBT with 30 min fasting and 4 h postprandial recording. In addition to standard metrics, the BSGM 'meal response ratio' (MRR) compared amplitude in the first 2 h postprandially to the subsequent 2 h (lagged meal response ≤ 1).

resultsOne hundred and forty-three patients underwent simultaneous BSGM and GEBT (79% female, median age 31 years, median BMI 23 kg/m

conclusionCombined BSGM and gastric emptying testing defines subgroups of gastroparesis based on several BSGM abnormalities, including a novel group with delayed postprandial onset of gastric motor activity in association with delayed emptying.

Indexed as

Gastric EmptyingGastroparesisStomachAdultBreath TestsFemaleHumansMaleMiddle AgedPostprandial PeriodYoung Adultelectrophysiologygastroparesismotilityphenotyping

Identifiers

PMID40720693
PMCPMC12534583

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.