Evidence map›Paper›PMID 40721870›Full record

ReviewCellular & molecular immunology2025

Myeloid cells in chronic liver inflammation.

Dimitrios Patseas, Ahmed El-Masry, Zuobin Liu, Prakash Ramachandran, Evangelos Triantafyllou

Abstract readReview
In one paragraph

Review in Cellular & molecular immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Donor-Specific Blood Transfusion Induces a Transfusion-Related Early Protective Effect in Murine Lung Transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dimitrios PatseasSection of Hepatology and Gastroenterology, Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.
Ahmed El-MasrySection of Hepatology and Gastroenterology, Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.
Zuobin LiuSection of Hepatology and Gastroenterology, Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.
Prakash RamachandranCentre for Inflammation Research, Institute for Regeneration and Repair, Edinburgh BioQuarter, University of Edissnburgh, Edinburgh, UK.
Evangelos TriantafyllouSection of Hepatology and Gastroenterology, Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK. e.triantafyllou@imperial.ac.uk.ORCID 0000-0002-2755-9619

Funding

RCUK | Medical Research Council (MRC) MR/W015919/1RCUK | Medical Research Council (MRC) MR/X009904/1
6 · The paper itself

Abstract

Chronic liver disease represents a significant global health burden. Regardless of etiology, its pathogenesis is driven by persistent liver inflammation, which can lead to fibrosis, cirrhosis, and an increased risk of cancer development. Myeloid cells, including neutrophils, eosinophils, monocytes, macrophages, and dendritic cells, play diverse and critical roles in hepatic immunity and the maintenance of tissue homeostasis but are also involved in liver injury, disease progression, and resolution. With the emergence of high-resolution omics technologies and in vivo fate-mapping models, our understanding of myeloid cell ontogeny and functional heterogeneity has been significantly refined. In this review, we discuss current insights into the myeloid cell landscape in nonviral chronic liver inflammatory conditions and summarize the roles of myeloid cell subsets in disease pathogenesis.

Indexed as

InflammationLiverMyeloid CellsAnimalsChronic DiseaseHumansDendritic cellsLiver cancerLiver fibrosisLiver inflammationMacrophagesNeutrophils

Identifiers

PMID40721870
PMCPMC12479923

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.