Evidence map›Paper›PMID 40721973›Full record

ArticleNature aging2025

Dietary patterns and accelerated multimorbidity in older adults.

David Abbad-Gomez, Adrián Carballo-Casla, Giorgi Beridze, Esther Lopez-Garcia, Fernando Rodríguez-Artalejo, Maria Sala, Mercè Comas, Davide Liborio Vetrano, Amaia Calderón-Larrañaga

Abstract read
In one paragraph

Article in Nature aging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

David Abbad-Gomez *Department of Epidemiology and Evaluation, Hospital del Mar, Barcelona, Spain. david.abbad.gomez@hmar.cat.ORCID http://orcid.org/0009-0004-6287-0076
Adrián Carballo-Casla *Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden. adrian.carballo.casla@ki.se.ORCID http://orcid.org/0000-0001-9401-9869
Giorgi BeridzeAging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden.
Esther Lopez-GarciaCenter for Networked Biomedical Research in Epidemiology and Public Health (CIBERESP), Madrid, Spain.
Fernando Rodríguez-ArtalejoCenter for Networked Biomedical Research in Epidemiology and Public Health (CIBERESP), Madrid, Spain.
Maria SalaDepartment of Epidemiology and Evaluation, Hospital del Mar, Barcelona, Spain.
Mercè ComasDepartment of Epidemiology and Evaluation, Hospital del Mar, Barcelona, Spain.
Davide Liborio VetranoAging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden.ORCID http://orcid.org/0000-0002-3099-4830
Amaia Calderón-LarrañagaAging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden.ORCID http://orcid.org/0000-0001-9064-9222

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diet could influence disease development and shape multimorbidity trajectories. Here we examined how four dietary patterns relate to 15-year multimorbidity accumulation in 2,473 community-dwelling older adults from the Swedish SNAC-K cohort. Multimorbidity was operationalized as the total number of chronic conditions and grouped into three organ systems. Higher adherence to the Mediterranean-DASH Diet Intervention for Neurodegenerative Delay, the Alternative Healthy Eating Index and the Alternative Mediterranean Diet was inversely associated with the annual rate of total chronic disease accumulation (β coefficient (95% confidence interval) per 1-s.d. increment: -0.049 (-0.065 to -0.032), -0.051 (-0.068 to -0.035) and -0.031 (-0.048 to -0.014), respectively), whereas higher adherence to the Empirical Dietary Inflammatory Index was associated with a faster rate of accumulation (0.053 (0.035-0.071)). Similar associations were observed for cardiovascular and neuropsychiatric diseases but not for musculoskeletal diseases. Some associations varied by sex and age. Our findings support diet quality as a modifiable risk factor for multimorbidity progression in older adults, with possible implications for dietary guidelines, public health strategies and clinical practice.

Indexed as

DietMultimorbidityAgedAged, 80 and overChronic DiseaseCohort StudiesDiet, MediterraneanFemaleHumansIndependent LivingMaleRisk FactorsSweden

Identifiers

PMID40721973
PMCPMC12350159

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.