Evidence mapPaperPMID 40722725Full record

ReviewBiomedicines2025

Precision Medicine in Hematologic Malignancies: Evolving Concepts and Clinical Applications.

Rita Khoury, Chris Raffoul, Christina Khater, Colette Hanna

Abstract readReview
In one paragraph

Review in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rita KhouryDivision of Hematology/Oncology, Lebanese American University Medical Center-Rizk Hospital, Beirut 1100, Lebanon.ORCID 0009-0001-2696-3580
Chris RaffoulDepartment of Internal Medicine at VCU Health, Richmond, VA 23298, USA.ORCID 0009-0005-9804-9658
Christina KhaterDivision of Hematology/Oncology, Lebanese American University Medical Center-Rizk Hospital, Beirut 1100, Lebanon.
Colette HannaDivision of Hematology/Oncology, Lebanese American University Medical Center-Rizk Hospital, Beirut 1100, Lebanon.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Precision medicine is transforming hematologic cancer care by tailoring treatments to individual patient profiles and moving beyond the traditional "one-size-fits-all" model. This review outlines foundational technologies, disease-specific advances, and emerging directions in precision hematology. The field is enabled by molecular profiling techniques, including next-generation sequencing (NGS), whole-exome sequencing (WES), and RNA sequencing (RNA-seq), as well as epigenomic and proteomic analyses. Complementary tools such as liquid biopsy and minimal residual disease (MRD) monitoring have improved diagnosis, risk stratification, and therapeutic decision making. We discuss major molecular targets and personalized strategies across hematologic malignancies:

Indexed as

artificial intelligencegenomic profilinghematologic malignanciesimmunotherapyliquid biopsyminimal residual diseaseprecision medicinetargeted therapy

Identifiers

PMID40722725
PMCPMC12292076

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.