Evidence map›Paper›PMID 40722802›Full record

ArticleBiomedicines2025

Novel Benzenesulfonamide Derivatives of 5'-Aminospirotriazolotriazine Exhibit Anti-Inflammatory Activity by Suppressing Pro-Inflammatory Mediators: In Vitro and In Vivo Evaluation Using a Rat Model of Carrageenan-Induced Paw Edema.

Amany M Hamed, Souhaila S Enaili, Walaa I Mohammed, Azza M A Abouelella, Zeyad Elsayed Eldeeb Mohana, Dina M Monir, Safaa S Soliman, Elsayed Eldeeb Mehana Hamouda, Hytham Mahmoud Abd Elatif, Ahmed M El-Saghier

Abstract read
In one paragraph

Article in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Development of Wedelia (Current issues in molecular biology · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Amany M HamedChemistry Department, Faculty of Science, Sohag University, Sohag 82524, Egypt.ORCID 0000-0002-5995-8358
Souhaila S EnailiPharmaceutical Chemistry Department, Faculty of Pharmacy, University of Zawia, Al Zawia 16418, Libya.ORCID 0009-0006-4254-7137
Walaa I MohammedDepartment of Clinical Pharmacology, Faculty of Medicine, Sohag University, Sohag 82524, Egypt.
Azza M A AbouelellaDepartment of Clinical Pharmacology, Faculty of Medicine, Sohag University, Sohag 82524, Egypt.
Zeyad Elsayed Eldeeb MohanaCollege of Medicine, Alexandria University, Alexandria 26571, Egypt.ORCID 0009-0006-5673-2018
Dina M MonirPhysiology Department, Faculty of Medicine, Sohag University, Sohag 82524, Egypt.
Safaa S SolimanDepartment of Zoology, Faculty of Science, Minia University, Minya 61519, Egypt.
Elsayed Eldeeb Mehana HamoudaDepartment of Pathology, College of Veterinary Medicine, Alexandria University, Alexandria 26571, Egypt.ORCID 0000-0002-7567-8049
Hytham Mahmoud Abd ElatifDepartment of Clinical Pharmacology, Faculty of Medicine, Sohag University, Sohag 82524, Egypt.ORCID 0009-0007-8319-171X
Ahmed M El-SaghierChemistry Department, Faculty of Science, Sohag University, Sohag 82524, Egypt.ORCID 0000-0002-4338-1486

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

1,3,5-triazine derivativesanti-inflammatorycarrageenancox isoenzymesindomethacinMTT assay

Identifiers

PMID40722802
PMCPMC12292862

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.