Sleep Disorders in Children with Rett Syndrome.

Christopher Harner, Thomas A Gaffey, Shannon S Sullivan, Manisha Witmans, Lourdes M DelRosso, Mary Anne Tablizo

Abstract readReview

In one paragraph

Review in Children (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Christopher HarnerCollege of Science, California State University, Turlock, CA 95382, USA.

Thomas A GaffeyDepartment of Psychology, University of Notre Dame, Notre Dame, IN 46556, USA.

Shannon S SullivanDivision of Pediatric Pulmonology and Sleep Medicine, Department of Pediatrics, School of Medicine Stanford, Stanford University, Lucile Packard Children's Hospital, Stanford, CA 94305, USA.

Manisha WitmansDivision of Pulmonology, Department of Pediatrics, University of Alberta, Edmonton, AB T6G 2R3, Canada.

Lourdes M DelRossoDivision of Sleep Medicine, Department of Internal Medicine, UCSF, Fresno, CA 93701, USA.ORCID 0000-0003-3349-8426

Mary Anne TablizoDivision of Pediatric Pulmonology and Sleep Medicine, Department of Pediatrics, School of Medicine Stanford, Stanford University, Lucile Packard Children's Hospital, Stanford, CA 94305, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rett syndrome (RTT) is an X-linked neurodevelopmental disorder marked by neurological regression, autonomic dysfunction, seizures, and significant sleep and breathing abnormalities. About 80% of affected individuals, especially young children, experience sleep disturbances such as insomnia, sleep-disordered breathing, nocturnal vocalizations, bruxism, and seizures. Breathing irregularities during sleep-like apnea, alternating hyperventilation, and hypoventilation-are common, with both obstructive and central sleep apnea identified through polysomnography. This review focuses on the prevalent sleep disorders in children with Rett syndrome and highlights current recommendations for the management of sleep disorders.

Indexed as

neurodevelopmental disorderRett syndromesleep disorder

Identifiers

PMID40723062

DOI10.3390/children12070869

PMCPMC12293099

What Socratic holds

Textmetadata

LicenceCC BY

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.