Evidence map›Paper›PMID 40724099›Full record

ArticleInternational journal of environmental research and public health2025

Neonatal Jaundice Treatment Versus Recommendations: The Challenge of Treatment Without Rapid Diagnostic Capability.

Ashura Bakari, Ann V Wolski, Benjamin Otoo, Rexford Amoah, Elizabeth Kaselitz, Sarah D Compton, Rebekah Shaw, Cheryl A Moyer

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of environmental research and public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ashura BakariDepartment of Child Health, Suntreso Government Hospital, Ghana Health Service, Kumasi AK-039, Ghana.ORCID 0000-0002-2277-2365
Ann V WolskiDepartments of Obstetrics and Gynecology, Pediatrics, and Learning Health Sciences, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Benjamin OtooDepartment of Child Health, Suntreso Government Hospital, Ghana Health Service, Kumasi AK-039, Ghana.
Rexford AmoahDepartment of Child Health, Suntreso Government Hospital, Ghana Health Service, Kumasi AK-039, Ghana.
Elizabeth KaselitzDepartments of Obstetrics and Gynecology, Pediatrics, and Learning Health Sciences, University of Michigan Medical School, Ann Arbor, MI 48109, USA.ORCID 0000-0001-7406-0995
Sarah D ComptonDepartments of Obstetrics and Gynecology, Pediatrics, and Learning Health Sciences, University of Michigan Medical School, Ann Arbor, MI 48109, USA.ORCID 0000-0002-1539-5397
Rebekah ShawDepartments of Obstetrics and Gynecology, Pediatrics, and Learning Health Sciences, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Cheryl A MoyerDepartments of Obstetrics and Gynecology, Pediatrics, and Learning Health Sciences, University of Michigan Medical School, Ann Arbor, MI 48109, USA.ORCID 0000-0002-5796-157X

Funding

NPGH LEADERs YR12: OBSSR (Greenberg, Ngwafong Mukere) & NIBIB (Lee)D43TW009345 · FIC · UNIVERSITY OF WASHINGTON · PI Dibyadyuti Datta, Chandy C. John · 2017 to 2026
$15.2M
FIC NIH HHS D43 TW009345NIH HHS 1D43TW009345-20A1
6 · The paper itself

Abstract

Neonatal jaundice (NNJ) is a leading cause of death in the early neonatal period, disproportionately affecting newborns in sub-Saharan Africa. In a setting without access to rapid assessment via transcutaneous bilirubin meter, we sought to determine how closely the diagnosis and treatment of neonatal jaundice at an urban district hospital aligned with retrospective assessment and treatment recommendations using the BiliApp (based on the UK NICE Guideline CG98). This retrospective chart review study aimed to identify: (1) What percent of admissions within 8 days of birth to the Mother and Baby Unit (MBU) at our study site were admitted for a primary diagnosis of neonatal jaundice, and what characterized those admissions? (2) How did treatment provided compare to the recommendations of the United Kingdom NICE Guideline CG98 via the "BiliApp"? and (3) Among those with jaundice, what factors were associated with an increased likelihood of severity indicative of the need for blood exchange therapy? The charts of all neonates admitted to the MBU at Suntreso Government Hospital (SGH), in Kumasi, Ghana, in 2020 were reviewed by trained research assistants. Data were collected regarding demographics, reason for admission, diagnostic markers (e.g., serum bilirubin level), treatments performed in the hospital, and outcome. Data were analyzed using Stata 18.0. There were 1059 newborns admitted to the MBU in 2020 at less than 8 days of age. A total of 179 (16.9%) were admitted with a primary diagnosis of neonatal jaundice. According to the BiliApp, 29.4% (

Indexed as

Jaundice, NeonatalBilirubinFemaleGhanaHumansInfant, NewbornMalePractice Guidelines as TopicRapid Diagnostic TestsRetrospective StudiesBilirubinAfricajaundicenewborn health

Identifiers

PMID40724099
PMCPMC12295268

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.