Evidence map›Paper›PMID 40724319›Full record

ArticleFoods (Basel, Switzerland)2025

Epicatechin Gallate Regulation of Steroid Hormone Levels Improves Sarcopenia in C57BL/6J Mice.

Ziwei Huang, Meifeng Liu, Yufei Zhou, Yiyu Tang, Jian'an Huang, Sheng Zhang, Zhonghua Liu, Ailing Liu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ziwei HuangCollege of Bioscience and Biotechnology, Hunan Agricultural University, Changsha 410128, China.
Meifeng LiuNational Research Center of Engineering and Technology for Utilization of Botanical Functional Ingredients, Changsha 410128, China.
Yufei ZhouNational Research Center of Engineering and Technology for Utilization of Botanical Functional Ingredients, Changsha 410128, China.
Yiyu TangNational Research Center of Engineering and Technology for Utilization of Botanical Functional Ingredients, Changsha 410128, China.ORCID 0009-0008-9308-9046
Jian'an HuangNational Research Center of Engineering and Technology for Utilization of Botanical Functional Ingredients, Changsha 410128, China.
Sheng ZhangNational Research Center of Engineering and Technology for Utilization of Botanical Functional Ingredients, Changsha 410128, China.
Zhonghua LiuNational Research Center of Engineering and Technology for Utilization of Botanical Functional Ingredients, Changsha 410128, China.
Ailing LiuCollege of Bioscience and Biotechnology, Hunan Agricultural University, Changsha 410128, China.

Funding

the National Key R&D Project and the Key R&D Project of Hunan Province 2022YFE0111200 and 2021NK1020-3
6 · The paper itself

Abstract

The decline in differentiation capacity during skeletal muscle (SkM) aging contributes to the deterioration of skeletal muscle function and impairs regenerative ability. Epicatechin gallate (ECG), a major functional component of catechins found in tea, has an unclear role in aging-related sarcopenia. In vivo experiments in 54-week-old C57BL/6J mice showed that ECG treatment improved exercise performance, muscle mass, and fiber morphology and downregulated the expression of the testosterone metabolic enzyme gene

Indexed as

epicatechin gallatesarcopeniaskeletal musclesteroid hormone

Identifiers

PMID40724319
PMCPMC12295562

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.