Evidence map›Paper›PMID 40724545›Full record

ArticleLife (Basel, Switzerland)2025

The ADVanced Organ Support (ADVOS) Hemodialysis System in Postoperative Cardiogenic Shock and Multiple Organ Failure: First Results in Cardiac Surgery Patients.

Veronika Walter, Ekaterina Hinrichs, Tarek Alloush, Aritz Perez Ruiz de Garibay, Gregor Warnecke, Wiebke Sommer, Hanna Gravert, Christina Grothusen, Janine Becker, Alexander Thiem and 1 more

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Veronika WalterDepartment of Cardiac Surgery, University Hospital Schleswig-Holstein, Campus Kiel, 24105 Kiel, Germany.
Ekaterina HinrichsDepartment of Cardiac Surgery, University Hospital Schleswig-Holstein, Campus Kiel, 24105 Kiel, Germany.
Tarek AlloushDepartment of Cardiac Surgery, University Hospital Schleswig-Holstein, Campus Kiel, 24105 Kiel, Germany.
Aritz Perez Ruiz de GaribayADVITOS GmbH, 80992 Munich, Germany.
Gregor WarneckeDepartment of Cardiac Surgery, University Hospital Schleswig-Holstein, Campus Kiel, 24105 Kiel, Germany.ORCID 0000-0002-4689-5714
Wiebke SommerDepartment of Cardiac Surgery, University Hospital Schleswig-Holstein, Campus Kiel, 24105 Kiel, Germany.
Hanna GravertDepartment of Cardiac Surgery, University Hospital Schleswig-Holstein, Campus Kiel, 24105 Kiel, Germany.
Christina GrothusenDepartment of Cardiac Surgery, University Hospital Schleswig-Holstein, Campus Kiel, 24105 Kiel, Germany.
Janine BeckerDepartment of Cardiac Surgery, University Hospital Schleswig-Holstein, Campus Kiel, 24105 Kiel, Germany.
Alexander ThiemDepartment of Cardiac Surgery, University Hospital Schleswig-Holstein, Campus Kiel, 24105 Kiel, Germany.
Bernd PanholzerDepartment of Cardiac Surgery, University Hospital Schleswig-Holstein, Campus Kiel, 24105 Kiel, Germany.ORCID 0000-0002-4992-818X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe management of multiple organ failure in the vulnerable cohort of cardiac surgery patients with cardiogenic shock remains a significant challenge, often impairing patient survival. A multimodal approach at targeting organ dysfunction seems to be a promising strategy, encompassing both hemodynamic support as well as differentiated organ replacement therapy. MATERIALS AND

methodsIn our retrospective study we examined the impact of the ADVOS (advanced organ support) system on overall outcomes and survival in an all-comers group of 22 cardiac surgery patients with postoperative cardiogenic shock and multiple organ failure.

aimsThe objective of the study was to assess the feasibility and potential benefits of ADVOS treatment in this patient population.

resultsThe standard care management in combination with ADVOS therapy corrected acid-base balance (pH 7.33 vs. 7.44,

conclusionsOur findings indicate that ADVOS treatment is both feasible and safe, with a substantial proportion of patients demonstrating improvements in organ function and overall outcomes.

Indexed as

cardiac surgerycardiogenic shockliver failure

Identifiers

PMID40724545
PMCPMC12300780

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.