Evidence map›Paper›PMID 40724646›Full record

ArticleLife (Basel, Switzerland)2025

Impact of Functional Therapy on Skeletal Structures and Airways in Patients with Class II Malocclusion: Comparison of Treatment in Prepubertal and Pubertal Phases.

Gianna Dipalma, Grazia Marinelli, Paola Bassi, Rosalba Lagioia, Francesca Calò, Mirka Cavino, Francesco Inchingolo, Franceska Vinjolli, Ioana Roxana Bordea, Giuseppe Minervini and 5 more

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Gianna DipalmaDepartment of Interdisciplinary Medicine, University of Bari Aldo Moro, 70124 Bari, Italy.ORCID 0000-0002-5947-8987
Grazia MarinelliDepartment of Interdisciplinary Medicine, University of Bari Aldo Moro, 70124 Bari, Italy.ORCID 0000-0001-9163-2350
Paola BassiDepartment of Interdisciplinary Medicine, University of Bari Aldo Moro, 70124 Bari, Italy.
Rosalba LagioiaDepartment of Interdisciplinary Medicine, University of Bari Aldo Moro, 70124 Bari, Italy.
Francesca CalòDepartment of Interdisciplinary Medicine, University of Bari Aldo Moro, 70124 Bari, Italy.
Mirka CavinoDepartment of Interdisciplinary Medicine, University of Bari Aldo Moro, 70124 Bari, Italy.
Francesco InchingoloDepartment of Interdisciplinary Medicine, University of Bari Aldo Moro, 70124 Bari, Italy.ORCID 0000-0003-3797-5883
Franceska VinjolliDepartment of Medical Sciences, Università Cattolica Nostra Signora del Buon Consiglio, Via Dritan Hoxha, 1001 Tirana, Albania.
Ioana Roxana BordeaDepartment of Oral Rehabilitation, Faculty of Dentistry, Iuliu Hațieganu University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.ORCID 0000-0001-7166-9949
Giuseppe MinerviniMultidisciplinary Department of Medical-Surgical and Odontostomatological Specialties, University of Campania Luigi Vanvitelli, 80121 Naples, Italy.ORCID 0000-0002-8309-1272
Sabina SaccomannoDepartment of Life, Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
Andrea PalermoDepartment of Experimental Medicine, University of Salento, 73100 Lecce, Italy.ORCID 0000-0002-3288-490X
Cinzia Maria Norma MasperoDepartment of Biomedical, Surgical and Dental Sciences, University of Milan, 20100 Milan, Italy.ORCID 0000-0002-5930-1698
Alessio Danilo InchingoloDepartment of Interdisciplinary Medicine, University of Bari Aldo Moro, 70124 Bari, Italy.ORCID 0000-0002-6366-1039
Angelo Michele InchingoloDepartment of Interdisciplinary Medicine, University of Bari Aldo Moro, 70124 Bari, Italy.ORCID 0000-0003-0104-6337

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to assess skeletal and upper airway modifications induced by the Twin Block appliance in patients with Class II malocclusion due to mandibular retrusion, using two-dimensional imaging techniques. A total of 11 patients (6 males, 5 females) were included and stratified into two groups (Pre-Peak and Peak) based on skeletal maturity evaluated through the cervical vertebral maturation (CVM) method. Lateral cephalometric radiographs were obtained at the beginning (T0) and end (T1) of treatment and analyzed using DeltaDent software. The appliance was worn full-time, except during meals and oral hygiene procedures, with monthly follow-ups. Significant changes were observed between T0 and T1 across the sample. Comparison between groups revealed statistically significant differences only in the H-C3a1 and vertical height (th) parameters (

Indexed as

class II malocclusionfunctional orthodonticsmandibular retrusionskeletal maturationTwin Block applianceupper airway

Identifiers

PMID40724646
PMCPMC12300978

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.