Evidence mapPaperPMID 40724883Full record

ReviewInternational journal of molecular sciences2025

Sirtuins Contribute to the Migraine-Stroke Connection.

Jan Krekora, Michal Fila, Maria Mitus-Kenig, Elzbieta Pawlowska, Justyna Ciupinska, Janusz Blasiak

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jan Krekora2nd Department of Cardiology, Medical University of Lodz, 92-213 Lodz, Poland.ORCID 0000-0002-7299-8442
Michal FilaDepartment of Developmental Neurology and Epileptology, Polish Mother's Memorial Hospital Research Institute, 93-338 Lodz, Poland.ORCID 0000-0002-0748-7080
Maria Mitus-KenigDepartment of Periodontology, Preventive Dentistry and Oral Pathology, Jagiellonian University, 31-532 Krakow, Poland.
Elzbieta PawlowskaDepartment of Pediatric Dentistry, Medical University of Lodz, 92-217 Lodz, Poland.ORCID 0000-0002-5373-4783
Justyna CiupinskaClinical Department of Infectious Diseases and Hepatology, H. Bieganski Hospital, 91-347 Lodz, Poland.
Janusz BlasiakFaculty of Medicine, Mazovian University in Plock, 09-240 Plock, Poland.ORCID 0000-0001-9539-9584

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prevalence of stroke in patients with migraine is higher than in the general population, suggesting certain shared mechanisms of pathogenesis. Migrainous infarction is a pronounced example of the migraine-stroke connection. Some cases of migraine with aura may be misdiagnosed as stroke, with subsequent mistreatment. Therefore, it is important to identify these shared mechanisms of pathogenesis contributing to the migraine-stroke connection to improve diagnosis and treatment. Sirtuins (SIRTs) are a seven-member family of NAD

Indexed as

Migraine DisordersSirtuinsStrokeAnimalsHumansMitochondriaOxidative StressSirtuinsmigrainemigraine–stroke connectionoxidative stresssirtuinsstroke

Identifiers

PMID40724883
PMCPMC12294337

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.