Evidence map›Paper›PMID 40725056›Full record

ArticleInternational journal of molecular sciences2025

Antimicrobial Composite Films Based on Alginate-Chitosan with Honey, Propolis, Royal Jelly and Green-Synthesized Silver Nanoparticles.

Corina Dana Dumitru, Cornelia-Ioana Ilie, Ionela Andreea Neacsu, Ludmila Motelica, Ovidiu Cristian Oprea, Alexandra Ripszky, Silviu Mirel Pițuru, Bianca Voicu Bălașea, Florica Marinescu, Ecaterina Andronescu

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Corina Dana DumitruDepartment of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Chemical Engineering and Biotechnology, National University of Science and Technology Politehnica Bucharest, 011061 Bucharest, Romania.
Cornelia-Ioana IlieDepartment of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Chemical Engineering and Biotechnology, National University of Science and Technology Politehnica Bucharest, 011061 Bucharest, Romania.ORCID 0000-0002-5504-5156
Ionela Andreea NeacsuDepartment of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Chemical Engineering and Biotechnology, National University of Science and Technology Politehnica Bucharest, 011061 Bucharest, Romania.ORCID 0000-0003-3197-6455
Ludmila MotelicaNational Research Center for Micro and Nanomaterials, National University of Science and Technology Politehnica Bucharest, 060042 Bucharest, Romania.ORCID 0000-0002-3371-4136
Ovidiu Cristian OpreaNational Research Center for Micro and Nanomaterials, National University of Science and Technology Politehnica Bucharest, 060042 Bucharest, Romania.ORCID 0000-0002-8145-1094
Alexandra RipszkyInterdisciplinary Center for Dental Research and Development, "Carol Davila" University of Medicine and Pharmacy, 6 Traian Vuia Str., 020956 Bucharest, Romania.ORCID 0000-0002-4345-282X
Silviu Mirel PițuruInterdisciplinary Center for Dental Research and Development, "Carol Davila" University of Medicine and Pharmacy, 6 Traian Vuia Str., 020956 Bucharest, Romania.
Bianca Voicu BălașeaInterdisciplinary Center for Dental Research and Development, "Carol Davila" University of Medicine and Pharmacy, 6 Traian Vuia Str., 020956 Bucharest, Romania.ORCID 0009-0002-7073-3309
Florica MarinescuThe Research Institute, University of Bucharest, 050663 Bucharest, Romania.
Ecaterina AndronescuDepartment of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Chemical Engineering and Biotechnology, National University of Science and Technology Politehnica Bucharest, 011061 Bucharest, Romania.ORCID 0000-0002-2226-5849

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Honey, propolis or royal jelly are considered natural remedies with therapeutic properties since antiquity. Many papers explore the development of antimicrobial biomaterials based on individual bee products, but there is a lack of studies on their synergistic effects. Combining honey, propolis and royal jelly with silver nanoparticles in a biopolymer matrix offers a synergistic strategy to combat antibiotic-resistant bacterial infections. This approach supports progress in wound healing, soft tissue engineering and other domains where elimination of the microorganisms is needed like food packaging. In this study we have obtained antimicrobial films based on bee products and silver nanoparticles (AgNPs) incorporated in an alginate-chitosan blend. The novel biomaterials were analyzed by UV-Vis, fluorescence and FTIR spectroscopy or microscopy, SEM and thermal analysis. Antibacterial tests were conducted against both Gram-positive and Gram-negative bacteria, while the antifungal properties were tested against

Indexed as

AlginatesAnti-Infective AgentsChitosanFatty AcidsHoneyMetal NanoparticlesPropolisSilverAnti-Bacterial AgentsCandida albicansGram-Negative BacteriaGram-Positive BacteriaGreen Chemistry TechnologyMicrobial Sensitivity TestsRoyal JellyAlginatesAnti-Bacterial AgentsAnti-Infective AgentsChitosanFatty AcidsPropolisRoyal JellySilverAg nanoparticlesantibacterialantifungalbiomaterialsgreen synthesishoneypropolisroyal jellywound healing

Identifiers

PMID40725056
PMCPMC12295747

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.