Evidence map›Paper›PMID 40725367›Full record

ReviewInsects2025

RNAi in Pest Control: Critical Factors Affecting dsRNA Efficacy.

Maribel Mendoza-Alatorre, Brenda Julian-Chávez, Stephanie Solano-Ornelas, Tania Samanta Siqueiros-Cendón, Jorge Ariel Torres-Castillo, Sugey Ramona Sinagawa-García, María Jazmín Abraham-Juárez, Carmen Daniela González-Barriga, Quintín Rascón-Cruz, Luis Ignacio Siañez-Estrada and 1 more

Abstract readReview
In one paragraph

Review in Insects, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Review
  2. EngineeredInsects · 2026
    Article
  3. Review
  4. Review
  5. Review
  6. Rethinking microbial biopesticide development and uptake.World journal of microbiology & biotechnology · 2026
    Review
  7. Review
  8. A Comprehensive Larval microRNA Atlas ofInternational journal of molecular sciences · 2026
    Article
  9. Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Research Progress on Diseases and Pests of Chrysanthemum (2015-2025).International journal of molecular sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Maribel Mendoza-AlatorreLaboratorio de Biotecnología I, Facultad de Ciencias Químicas, Universidad Autónoma de Chihuahua, Circuito Universitario S/N Nuevo Campus Universitario, Chihuahua C.P. 31125, Chihuahua, Mexico.ORCID 0000-0003-2938-0935
Brenda Julian-ChávezLaboratorio de Biotecnología I, Facultad de Ciencias Químicas, Universidad Autónoma de Chihuahua, Circuito Universitario S/N Nuevo Campus Universitario, Chihuahua C.P. 31125, Chihuahua, Mexico.ORCID 0009-0004-1425-0921
Stephanie Solano-OrnelasLaboratorio de Nanotoxicología y Genómica Funcional, Centro de Investigación en Materiales Avanzados S.C., Miguel de Cervantes 120, Complejo Industrial Chihuahua, Chihuahua C.P. 31136, Chihuahua, Mexico.ORCID 0009-0000-4785-3084
Tania Samanta Siqueiros-CendónLaboratorio de Biotecnología I, Facultad de Ciencias Químicas, Universidad Autónoma de Chihuahua, Circuito Universitario S/N Nuevo Campus Universitario, Chihuahua C.P. 31125, Chihuahua, Mexico.ORCID 0000-0002-9222-4145
Jorge Ariel Torres-CastilloInstituto de Ecología Aplicada, Universidad Autónoma de Tamaulipas, Ave. División del Golfo 356, Col. Libertad, Ciudad Victoria C.P. 87019, Tamaulipas, Mexico.ORCID 0000-0001-9311-7547
Sugey Ramona Sinagawa-GarcíaLaboratorio de Biotecnología, Facultad de Agronomía, Universidad Autónoma de Nuevo León, Francisco Villa S/N Col. Ex Hacienda El Canadá, General Escobedo C.P. 66050, Nuevo León, Mexico.ORCID 0000-0002-5961-0968
María Jazmín Abraham-JuárezUnidad de Genómica Avanzada, Centro de Investigación y de Estudios Avanzados del IPN, Libramiento Norte León Km 9.6, Irapuato C.P. 36821, Guanajuato, Mexico.ORCID 0000-0002-5468-8176
Carmen Daniela González-BarrigaLaboratorio de Cultivo de Tejidos, División de Ingeniería y Ciencias, Tecnológico de Monterrey, Av. Heroico Colegio Militar 4700, Nombre de Dios, Chihuahua C.P. 31100, Chihuahua, Mexico.ORCID 0000-0001-7889-0945
Quintín Rascón-CruzLaboratorio de Biotecnología I, Facultad de Ciencias Químicas, Universidad Autónoma de Chihuahua, Circuito Universitario S/N Nuevo Campus Universitario, Chihuahua C.P. 31125, Chihuahua, Mexico.ORCID 0000-0001-9879-5988
Luis Ignacio Siañez-EstradaLaboratorio de Biotecnología I, Facultad de Ciencias Químicas, Universidad Autónoma de Chihuahua, Circuito Universitario S/N Nuevo Campus Universitario, Chihuahua C.P. 31125, Chihuahua, Mexico.ORCID 0000-0001-5059-8424
Edward Alexander Espinoza-SánchezLaboratorio de Biotecnología I, Facultad de Ciencias Químicas, Universidad Autónoma de Chihuahua, Circuito Universitario S/N Nuevo Campus Universitario, Chihuahua C.P. 31125, Chihuahua, Mexico.ORCID 0000-0001-5040-0510

Funding

Consejo Nacional de Humanidades, Ciencias y Tecnologías (CONAHCYT), México CF-2023-I-1539
6 · The paper itself

Abstract

In recent years, agricultural crops have increasingly been attacked by more destructive insect pests, forcing modern farming to depend mainly on chemical insecticides. Although valuable, their widespread and intensive misuse has raised serious concerns about environmental and public health impacts. RNAi has been proposed as a safer alternative due to its high specificity, adaptability, and low ecological footprint. So far, dsRNA has proven effective in controlling various pest species, either through topical application or via genetically modified plants. Despite advances, large-scale implementation of RNAi remains challenging due to technical and biological hurdles that contribute to inconsistent performance. Key aspects such as dsRNA design, delivery techniques, and cellular uptake mechanisms still require refinement. Additionally, ensuring environmental stability, addressing biosafety concerns, and developing cost-effective production methods are essential for its practical application. In this review, we explore recent advances in the design and implementation of dsRNA, as well as the strategies that could support the successful integration of RNAi technology into pest management programs.

Indexed as

biological barriersdelivery methodsdesigndsRNApest managementRNA interference

Identifiers

PMID40725367
PMCPMC12295715

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.