Genomic Regions Associated with Respiratory Disease in Holstein Calves in the Southern United States.

Allison L Herrick, Jennifer N Kiser, Stephen N White, Holly L Neibergs

Abstract read

In one paragraph

Article in Genes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Runs of homozygosity in Italian Holstein bulls: a permutation approach and time-based mapping of the genomic regions potentially under selection.BMC genomics · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Allison L HerrickDepartment of Animal Sciences, Washington State University, Pullman, WA 99164, USA.ORCID 0009-0000-0436-4731

Jennifer N KiserDepartment of Animal Sciences, Washington State University, Pullman, WA 99164, USA.

Stephen N WhiteDepartment of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA 99164, USA.ORCID 0000-0001-9255-6054

Holly L NeibergsDepartment of Animal Sciences, Washington State University, Pullman, WA 99164, USA.ORCID 0000-0001-8121-3072

Funding

United States Department of Agriculture, National Institute of Food and Agriculture multi-state Hatch project NC-1192 and Hatch project WNP00007 Accession #1025787

6 · The paper itself

Abstract

BACKGROUND/

objectivesBovine respiratory disease (BRD) is a common disease impacting cattle throughout the US. BRD is a multifactorial disease as disease risk varies with the genetic profile of the host, environmental conditions, and pathogen exposure. Selection for enhanced BRD resistant cattle can aid in reducing BRD. The objectives of this study were to identify loci, gene sets, and genes associated and enriched for BRD in pre- and post-weaned Holstein cattle.

methodsCases consisted of 2147 and 5607 calves treated for BRD as pre-weaned (0-60 days old) and post-weaned (61-420 days old) calves, respectively. Controls consisted of calves untreated for BRD that remained in the herd for 61 (

resultsIn pre-weaned calves, 62 loci and 123 positional candidate genes were associated (

conclusionsThese results provide further insight and validation of genomic regions that enhance selection for BRD resistance and for healthier cattle.

Indexed as

Bovine Respiratory Disease ComplexAnimalsCattleGenetic Predisposition to DiseaseGenomeGenome-Wide Association StudyPolymorphism, Single Nucleotidebovine respiratory diseasecattlegene set enrichment analysisgenome wide association analysis

Identifiers

PMID40725399

DOI10.3390/genes16070741

PMCPMC12294756

What Socratic holds

Textmetadata

LicenceCC BY

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.