Evidence map›Paper›PMID 40726667›Full record

ArticleJournal of family medicine and primary care2025

Clinical and radiological evaluation of osteoarthritis in knee pain patients and its association with inflammatory markers at MGM Medical College Hospital, Jamshedpur.

Abhishek Guria, Vibhas Chandra, Bhaskar Bej, Kumar Vimal, Rajan K Barnwal, Uma S Singh, Kuber C Setua

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Article in Journal of family medicine and primary care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

What it found

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Abhishek GuriaDepartment of Orthopaedics, Rajendra Institute of Medical Science, Ranchi, Jharkhand, India.
Vibhas ChandraDepartment of Orthopaedics, MGM Medical College and Hospital, Jamshedpur, Jharkhand, India.
Bhaskar BejDepartment of Orthopaedics, MGM Medical College and Hospital, Jamshedpur, Jharkhand, India.
Kumar VimalMulti-Disciplinary Research Unit, MGM Medical College, Jamshedpur, Jharkhand, India.
Rajan K BarnwalDepartment of Community Medicine, Medinirai Medical College, Palamu, Jharkhand, India.
Uma S SinghDepartment of Pathology, MGM Medical College, Jamshedpur, Jharkhand, India.
Kuber C SetuaMulti-Disciplinary Research Unit, MGM Medical College, Jamshedpur, Jharkhand, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Context: Knee osteoarthritis, a global joint disorder, affects 22%-39% of the population, with a higher incidence in India among women aged 65 and above. Biochemical markers like cytokines could help detect and treat the disease, potentially reducing socioeconomic costs and enabling a transition from degenerative to mechanical stress-induced disease. Aims: To investigate the epidemiology of osteoarthritis in knee pain in adults, its clinical and radiological evaluation, and its association with inflammatory markers. Settings and Design: The Department of Orthopaedics at MGMMCH, Jamshedpur, conducted this cross-sectional study. Methods and Material: The study analyzed 170 patients with knee OA symptoms from August 2023 to February 2024, using the KOOS Knee Survey clinical criteria. We used the Kellgren and Lawrence scale for radiological diagnosis of knee osteoarthritis. Statistical Analysis Used: The study utilized descriptive statistics, Chi-square test, and bivariate Spearman's correlation, with statistical significance determined by Results: We found that the overall prevalence of knee Osteoarthritis was 70%. We discovered that 59.4% of us were male. The majority were aged 40-49 (32%), 50-59 (25.3%), and 30-39 (14.1%). The grade of knee pain showed a statistically significant strong positive correlation ( Conclusions: Knee osteoarthritis is prevalent in younger individuals, with males more affected. Elevated IL6, IL1β, and TNFα levels in meniscectomy patients increase osteoarthritis risk, potentially aiding targeted treatment.

Indexed as

Interleukin 1βInterleukin-6knee painosteoarthritistumor necrosis factor α

Identifiers

PMID40726667
PMCPMC12296253

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.