ReviewCureus2025
Association Between Gestational Diabetes Mellitus and Maternal Depression: A Narrative Review.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Serum Serotonin Levels and Postpartum Depression in Women with Gestational Diabetes Mellitus: A Prospective Psychobiological Study.Journal of clinical medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gestational diabetes mellitus (GDM) and maternal depression are increasingly recognized as interrelated conditions that significantly impact maternal and neonatal outcomes. This narrative review synthesizes current evidence on the bidirectional relationship between GDM and maternal depression, emphasizing their combined burden on perinatal health. GDM, characterized by glucose intolerance identified during pregnancy, is experiencing a rising global prevalence and is linked to an increased risk of depressive symptoms both during pregnancy and postpartum. Women diagnosed with GDM show a markedly higher incidence of depression compared to their non-GDM counterparts, influenced by factors such as metabolic dysregulation, inflammatory pathways, and the psychosocial stressors associated with managing a high-risk pregnancy. Moreover, maternal depression in the context of GDM is associated with suboptimal glycemic control, a higher incidence of obstetric complications, and diminished maternal quality of life. Fetal risks, including preterm birth, abnormal birth weight, and adverse neurodevelopmental outcomes, are heightened when maternal depression coexists with GDM. Biological mechanisms, such as dysregulation of the hypothalamic-pituitary-adrenal axis, insulin resistance, and chronic inflammation, provide plausible connections between these conditions. The evidence highlights the necessity for integrated, multidisciplinary care models that incorporate routine mental health screenings within GDM management protocols. Early identification and intervention for depressive symptoms, along with patient education and psychosocial support, are critical to improving clinical outcomes. This review advocates for holistic, culturally sensitive approaches and calls for further longitudinal research to elucidate the underlying mechanisms and enhance perinatal care strategies that address both the metabolic and psychological aspects of maternal health.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.