ArticleJournal of the American Heart Association2025
Moderate Kidney Dysfunction Independently Increases Sudden Cardiac Arrest Risk: A Community-Based Study.
Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- Mortality Trends Involving Cardiac Arrest and Fluid, Electrolyte, and Acid-Base Disorders in U.S. Adults, 2004-2024.Journal of clinical medicine · 2026Article
- Interplay Between Fibroblast Growth Factor-19, Beta-Klotho, and Receptors Impacts Cardiovascular Risk in Chronic Kidney Disease.Journal of clinical medicine · 2026Article
- Beyond cardiac risk factors: non-cardiovascular comorbidities in sudden cardiac death prediction.Frontiers in cardiovascular medicine · 2026Review
- Dietary inflammatory index in relation to incident CKD: A prospective study of UK Biobank participants.PloS one · 2026Article
- Exploring the stroke burden linked to Kidney dysfunction: trends, predictive insights, and health inequalities.Frontiers in neurology · 2025Article
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8 authors.
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Abstract
backgroundModerate kidney dysfunction is independently associated with increased cardiovascular death. Sudden cardiac arrest (SCA) accounts for at least 25% of chronic kidney disease (CKD) death. This study aimed to evaluate the impact of moderate CKD on SCA risk.
methodsWe conducted a case-control study within a community-based investigation of SCA in the Portland, Oregon, metropolitan area from February 1, 2002, to December 31, 2020. Analysis included individuals aged 40 to 75 years who experienced SCA (cases) and individuals with no history of SCA (controls), with creatinine levels measured before SCA/enrollment. Moderate CKD was defined by an estimated glomerular filtration rate of 30 to <60 mL/min per 1.73 m
resultsWe compared 2068 SCA cases and 852 controls (mean ages, 61.4±8.5 and 62.7±8.0 years, respectively; men: 69.9% and 67.4%, respectively). SCA cases had more moderate CKD (17.7% versus 14.7%,
conclusionsModerate CKD is associated with an increased risk of SCA in the general population. Further research into the potential integration of moderate renal dysfunction into SCA risk stratification are warranted.
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