Evidence map›Paper›PMID 40729027›Full record

ArticleCurrent issues in molecular biology2025

Evodiamine Boosts AR Expression to Trigger Senescence and Halt Proliferation in OSCC Cells.

Gang Chen, Hong-Liang Du, Jia-Nan Liu, Jie Cheng, Jing Chen, Xiao-Yang Yin, Hu-Lai Wei, Jing Wang

Abstract read
In one paragraph

Article in Current issues in molecular biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gang ChenSchool of Basic Medical Sciences, Lanzhou University, Lanzhou 730000, China.ORCID 0009-0005-7010-8257
Hong-Liang DuThe First Hospital of Lanzhou University, Lanzhou 730000, China.
Jia-Nan LiuGeneral Practitioner Primary Training Base of the First Hospital of Lanzhou University, Lanzhou 730000, China.
Jie ChengSchool of Basic Medical Sciences, Lanzhou University, Lanzhou 730000, China.
Jing ChenSchool of Basic Medical Sciences, Lanzhou University, Lanzhou 730000, China.
Xiao-Yang YinSchool of Basic Medical Sciences, Lanzhou University, Lanzhou 730000, China.
Hu-Lai WeiSchool of Basic Medical Sciences, Lanzhou University, Lanzhou 730000, China.ORCID 0000-0001-8566-177X
Jing WangHospital of Stomatology, Lanzhou University, Lanzhou 730000, China.

Funding

Medical Scientific Research Innovation Capacity Improvement Project of Lanzhou University lzuyxcx-2022-182Natural Science Foundation of Gansu Province 22JR5RA1064Scientific and Technological Foundation of Gansu Province 25JRRA1284 and 20JR10FA670
6 · The paper itself

Abstract

Oral squamous cell carcinoma (OSCC), an aggressive and poorly prognosed subtype of head and neck squamous cell carcinoma (HNSCC), has prompted urgent calls for innovative therapeutic approaches. Evodiamine (EVO), a natural alkaloid extracted from the Chinese herb

Indexed as

androgen receptorevodiamineoral squamous cell carcinomasenescence

Identifiers

PMID40729027
PMCPMC12293151

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.