Evidence map›Paper›PMID 40730190›Full record

ArticleCell reports. Medicine2025

Tumor-specific CD8 T cell characterization in HR

Mariana Pereira Pinho, Elie Antoun, Balraj Sandhar, Ting Shu, Fei Gao, Xiaobao Yang, Adam Bates, Lucia Cerundolo, Megat H B A Hamid, David Maldonado-Perez and 16 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell reports. Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Mariana Pereira PinhoMedical Research Council Translational Immune Discovery Unit (MRC TIDU), Weatherall Institute of Molecular Medicine (WIMM), University of Oxford, Oxford, UK; Chinese Academy of Medical Sciences (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK.
Elie AntounChinese Academy of Medical Sciences (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK; Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Balraj SandharMedical Research Council Translational Immune Discovery Unit (MRC TIDU), Weatherall Institute of Molecular Medicine (WIMM), University of Oxford, Oxford, UK; Chinese Academy of Medical Sciences (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK.
Ting ShuChinese Academy of Medical Sciences (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK.
Fei GaoMedical Research Council Translational Immune Discovery Unit (MRC TIDU), Weatherall Institute of Molecular Medicine (WIMM), University of Oxford, Oxford, UK; Chinese Academy of Medical Sciences (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK.
Xiaobao YangChinese Academy of Medical Sciences (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK.
Adam BatesMedical Research Council Translational Immune Discovery Unit (MRC TIDU), Weatherall Institute of Molecular Medicine (WIMM), University of Oxford, Oxford, UK; Chinese Academy of Medical Sciences (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK.
Lucia CerundoloNuffield Department of Surgical Sciences, University of Oxford, John Radcliffe Hospital, Oxford, UK.
Megat H B A HamidChinese Academy of Medical Sciences (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK.
David Maldonado-PerezNuffield Department of Surgical Sciences, University of Oxford, John Radcliffe Hospital, Oxford, UK.
Renuka TeagueNuffield Department of Surgical Sciences, University of Oxford, John Radcliffe Hospital, Oxford, UK.
Eve WarnerNuffield Department of Surgical Sciences, University of Oxford, John Radcliffe Hospital, Oxford, UK.
Lucinda WinterDepartment of Cellular Pathology, Oxford University NHS Foundation Trust, Oxford, UK.
Nasullah Khalid AlhamInstitute of Biomedical Engineering, Department of Engineering Science, University of Oxford, Oxford, UK; Oxford National Institute of Health Research (NIHR) Biomedical Research Centre, John Radcliffe Hospital, Oxford, UK.
Clare VerrillNuffield Department of Surgical Sciences, University of Oxford, John Radcliffe Hospital, Oxford, UK; Oxford National Institute of Health Research (NIHR) Biomedical Research Centre, John Radcliffe Hospital, Oxford, UK.
Simon R LordDepartment of Oncology, University of Oxford, Oxford, UK.
Timothy RostronSequencing Facility, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
Sally-Ann ClarkFlow Cytometry Facility, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
Craig WaughFlow Cytometry Facility, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
Paul SoppFlow Cytometry Facility, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
Chris ConlonChinese Academy of Medical Sciences (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK.
Ricardo A FernandesChinese Academy of Medical Sciences (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK.
Adrian L HarrisDepartment of Oncology, University of Oxford, Oxford, UK.
Yanchun PengMedical Research Council Translational Immune Discovery Unit (MRC TIDU), Weatherall Institute of Molecular Medicine (WIMM), University of Oxford, Oxford, UK; Chinese Academy of Medical Sciences (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK.
Asha AdwaniDepartment of Breast Surgery, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Tao DongMedical Research Council Translational Immune Discovery Unit (MRC TIDU), Weatherall Institute of Molecular Medicine (WIMM), University of Oxford, Oxford, UK; Chinese Academy of Medical Sciences (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK. Electronic address: tao.dong@ndm.ox.ac.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Most breast cancers express the estrogen receptor (ER), but the immune response of hormone receptor-positive (HR

Indexed as

Breast NeoplasmsCD8-Positive T-LymphocytesReceptors, EstrogenDendritic CellsFemaleHumansLymphatic MetastasisLymph NodesLymphocytes, Tumor-InfiltratingMiddle AgedReceptors, Antigen, T-CellReceptors, Antigen, T-CellReceptors, Estrogenantitumor CD8 T cellscancer testis antigenCDR3CTAER+ breast cancermetastatic luminal breast cancermoDCT cell receptorT cell repertoiretumor lysatetumor-specific T cells

Identifiers

PMID40730190
PMCPMC12432377

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.