Evidence map›Paper›PMID 40730399›Full record

Observational studyBMJ open2025

Follow-up rescreening uptake and persistent positive rates among women after positive cervical cancer screening results in Ethiopia: a longitudinal cross-sectional study.

Alemnew Destaw, Sefonias Getachew, Eyerusalem Getachew, Abel Shita, Miresa Midaksa, Sophie Sarah Rossner, Eric Sven Kroeber, Adamu Addissie, Eva Johanna Kantelhardt, Muluken Gizaw

Registry-linked trialAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06515301 (Key Interventions to Improve the Follow-up Adherence Post Cervical Precancerous Lesion Treatment in Ethiopia), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06515301 narecruitingnot on this map

Key Interventions to Improve the Follow-up Adherence Post Cervical Precancerous Lesion Treatment in Ethiopia: A Pragmatic Randomized Controlled Trial

TypeinterventionalSponsorAddis Ababa UniversityRan2024 to 2025Enrolled466ConditionsSuspicious Cervical Cancer Lesions Follow up AdherenceArmsIntervention 1: Structured nurse-led telephone call reminders. Intervention 2: Home-visit reminders by health extension workers. Intervention 3: Application-based automated SMS text reminders.
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alemnew DestawSchool of Public Health, Mizan-Tepi University, Mizan-Teferi, Ethiopia.ORCID http://orcid.org/0000-0002-7504-3924
Sefonias GetachewGlobal Health Working Group, Institute of Medical Epidemiology, Biometrics and Informatics, Martin Luther University Halle Wittenberg, Halle, Germany.ORCID http://orcid.org/0000-0001-9506-1196
Eyerusalem GetachewGlobal Health Working Group, Institute of Medical Epidemiology, Biometrics and Informatics, Martin Luther University Halle Wittenberg, Halle, Germany.
Abel ShitaGlobal Health Working Group, Institute of Medical Epidemiology, Biometrics and Informatics, Martin Luther University Halle Wittenberg, Halle, Germany.
Miresa MidaksaGlobal Health Working Group, Institute of Medical Epidemiology, Biometrics and Informatics, Martin Luther University Halle Wittenberg, Halle, Germany.
Sophie Sarah RossnerGlobal Health Working Group, Institute of Medical Epidemiology, Biometrics and Informatics, Martin Luther University Halle Wittenberg, Halle, Germany.
Eric Sven KroeberGlobal Health Working Group, Institute of Medical Epidemiology, Biometrics and Informatics, Martin Luther University Halle Wittenberg, Halle, Germany.
Adamu AddissieGlobal Health Working Group, Institute of Medical Epidemiology, Biometrics and Informatics, Martin Luther University Halle Wittenberg, Halle, Germany.
Eva Johanna Kantelhardt *Global Health Working Group, Institute of Medical Epidemiology, Biometrics and Informatics, Martin Luther University Halle Wittenberg, Halle, Germany.ORCID http://orcid.org/0000-0001-7935-719X
Muluken Gizaw *Global Health Working Group, Institute of Medical Epidemiology, Biometrics and Informatics, Martin Luther University Halle Wittenberg, Halle, Germany muluken.gizaw@aau.edu.et.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess cervical cancer screening positivity rates, follow-up rescreening uptake 1 year after treatment and persistent positivity among women with initial positive screening results in Ethiopia. The study also explored reasons for loss to follow-up and preferences for reminder strategies.

designLongitudinal cross-sectional study. SETTINGS: 10 primary healthcare facilities in Oromia and southern and central Ethiopia.

participantsFrom November 2022 to April 2024, 17 586 women screened for cervical cancer. Of these 768 (4.4%) had positive screening results, and 515 women treated at the primary level were included to assess follow-up rescreening uptake. An additional 139 women who did not return for follow-up were interviewed to identify reasons for non-uptake and reminder preferences.

resultOf the 515 women included in the analysis, 179 (34.8%, 95% CI: 30.6% to 38.8%) returned for follow-up rescreening. Among those re-screened, the persistent visual inspection with acetic acid (VIA) positivity rate was 16.1% (95% CI: 11.0% to 21.7%). Factors significantly associated with follow-up rescreening uptake included age over 40 (adjusted OR (AOR): 2.5; 95% CI: 1.34 to 5.00), urban residence (AOR: 1.7; 95% CI: 1.15 to 2.58), secondary or higher education (AOR: 2.0; 95% CI: 1.06 to 4.12) and HIV-positive status (AOR: 2.4; 95% CI: 1.27 to 4.87). Among the 139 women contacted, the main reasons for non-uptake were lack of time, forgetting appointments, visiting another facility and pregnancy. Regarding preferred reminders, 93% favoured text messages and all agreed to phone calls or home visits.

conclusionOne-third of women adhered to follow-up rescreening after a positive cervical cancer screening in Ethiopia, revealing a considerable gap since those women had a three times higher chance of being VIA positive compared with the first screening. Older age, urban residence, higher education and HIV-positive status were significantly linked to follow-up rescreening uptake. Addressing barriers such as time constraints and forgotten appointments through tailored reminder strategies is essential for improving the follow-up rescreening uptake. Contextualised interventions can strengthen rescreening for finding those women at very high risk for cervical lesions and strengthen cervical cancer prevention in Ethiopia. TRIAL REGISTRATION NUMBER: NCT06515301.

Indexed as

Early Detection of CancerPatient Acceptance of Health CareUterine Cervical NeoplasmsAdultCross-Sectional StudiesEthiopiaFemaleHumansLongitudinal StudiesMass ScreeningMiddle AgedPragmatic Clinical Trials as TopicReminder SystemsYoung AdultEthiopiaFollow-Up StudiesObservational StudyUterine Cervical Neoplasms

Identifiers

PMID40730399
PMCPMC12306462

What Socratic holds

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LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.