ArticleBJC reports2025
Long-term outcomes of consecutive patients of oropharyngeal cancer treated with radical radiotherapy.
Article in BJC reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Prognostic Factors in Oropharyngeal Cancer Treated With Definitive Chemoradiotherapy.Cancer medicine · 2026Article
- Divergent immuno-landscapes: comparing the tumor microenvironment of Indian and Western HNSCC patients.Frontiers in cell and developmental biology · 2026Review
- Silibinin Triggers Mitochondrial Apoptosis and Declines Clonogenic Potential in Detroit 562 Human Pharyngeal Carcinoma Cells.Medicina (Kaunas, Lithuania) · 2025Article
- Article
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Authors and funding
20 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesGiven the wide variation in the incidence of Human Papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma (OPSCC), we aimed to evaluate the prevalence of HPV and assess treatment outcomes in patients with OPSCC treated with definitive radiotherapy (RT) with or without chemotherapy (CT) at a single institution in India.
methodsConsecutive patients of OPSCC treated with definitive RT + /-CT in a tertiary care centre from January 2013 to December 2017 were analyzed. Kaplan-Meier method was used for survival analysis, and Log-rank test was used for univariate analysis.
resultsSix-hundred-thirty patients with OPSCC were treated with definitive RT + /-CT. The median age was 56 years (IQR 48-62). As per American Joint Committee on Cancer (AJCC) 7
conclusionThe prevalence of HPV-positive OPSCC by p16 IHC was only 11% in our cohort. The outcomes of HPV-negative cancers are inferior when compared to HPV-positive cancers for a particular stage. Thereby justifying the need for development of treatment-intensifying strategies to improve the inferior outcomes.
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Registered trials
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