ArticleBMC nephrology2025
Effects of the pretransplant obesity on kidney transplant outcomes in Korea: a nationwide cohort study.
Article in BMC nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors.
Funding
Abstract
backgroundThe prevalence of obesity is steadily increasing in patients with end-stage kidney disease. However, it is still debatable whether obesity affects outcomes after kidney transplantation. This study evaluated the relationship between pretransplant obesity, defined as a body mass index (BMI) ≥ 25 kg/m
methodsWe investigated prospective nationwide cohort data from the Korean Organ Transplantation Registry (KOTRY) from 2014 to 2021. KTRs were categorized into 4 groups based on pretransplant BMI: underweight (< 18.5), normal weight (18.5-22.9), overweight (23-24.9), and obesity (≥ 25). Posttransplant outcomes, including death-censored allograft loss, cardiovascular events, and all-cause mortality, were compared using Kaplan-Meier curves with the log-rank test. Cox proportional hazard regression analysis was employed to assess associations between BMI and posttransplant outcomes.
resultsA total of 9,130 KTRs were finally analyzed. The mean age was 49.9 ± 11.6 and 60.2% of KTRs were male. The prevalence of obesity in KTRs was 28.6% and continued to increase (24.8% in 2014 to 32.5% in 2021). Obese KTRs were characterized by male predominance, shorter dialysis vintage, and more diabetes as primary kidney disease. Kaplan-Meier curve showed a significant difference in death-censored allograft loss among BMI groups (P = 0.007). Obesity (BMI ≥ 25 kg/m²) was as an independent risk factor for death-censored allograft loss (adjusted hazard ratio 1.511, 95% confidence interval 1.063-2.148, P = 0.021), but not for cardiovascular events or mortality.
conclusionsOur study evaluated BMI across a spectrum of categories, suggesting that obesity is an independent risk factor for graft survival in KTRs. Risk stratification using BMI and strategies to prevent obesity should be considered in the preparation for kidney transplantation. CLINICAL TRIAL NUMBER: Not applicable.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.