Evidence map›Paper›PMID 40731809›Full record

ReviewMedicina (Kaunas, Lithuania)2025

Retinitis Pigmentosa: From Genetic Insights to Innovative Therapeutic Approaches-A Literature Review.

Ricardo A Murati Calderón, Andres Emanuelli, Natalio Izquierdo

Abstract readReview
In one paragraph

Review in Medicina (Kaunas, Lithuania), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Ciliary Defects in Inherited Retinal Diseases.Advanced genetics (Hoboken, N.J.) · 2026
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ricardo A Murati CalderónDepartment of Ophthalmology, School of Medicine, University of Puerto Rico, San Juan 00936-5067, Puerto Rico.ORCID 0009-0003-2610-4019
Andres EmanuelliDepartment of Ophthalmology, School of Medicine, University of Puerto Rico, San Juan 00936-5067, Puerto Rico.
Natalio IzquierdoDepartment of Surgery, University of Puerto Rico, Medical Sciences Campus, San Juan 00936-5067, Puerto Rico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Retinitis pigmentosa (RP) is a heterogeneous group of inherited retinal dystrophies characterized by progressive photoreceptor degeneration and vision loss. While current management is largely supportive-relying on visual aids, orientation training, and nutritional supplementation-these interventions offer only symptomatic relief and do not halt disease progression. Advances in molecular genetics have led to the development of targeted treatments, including gene replacement therapy, RNA-based therapies, and CRISPR/Cas9 gene editing, offering promising strategies for disease modification. The approval of voretigene neparvovec for

Indexed as

Genetic TherapyRetinitis PigmentosaGene EditingHumanscell-based therapygene therapygeneticsinherited retinal diseasemultidisciplinary approachoptogeneticsretinal prostheticsretinitis pigmentosa

Identifiers

PMID40731809
PMCPMC12298941

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.