Evidence map›Paper›PMID 40732097›Full record

ArticleMicroorganisms2025

Discovery of 4,5,6,7-Tetrahydrothieno [3,2-b] Pyridine as Novel Fungicide Lead Scaffold.

Ke Chen, Difan Deng, Yupeng Yin, Dongmei Xi, Phumbum Park, Wei Gao, Rui Liu, Kang Lei

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ke ChenDepartment of Biotechnology, The University of Suwon, Hwaseong 18323, Gyeonggi-do, Republic of Korea.
Difan DengSchool of Pharmaceutical Sciences and Food Engineering, Liaocheng University, Liaocheng 252059, China.
Yupeng YinSchool of Pharmaceutical Sciences and Food Engineering, Liaocheng University, Liaocheng 252059, China.
Dongmei XiCollege of Life Sciences, Linyi University, Linyi 276005, China.
Phumbum ParkDepartment of Biotechnology, The University of Suwon, Hwaseong 18323, Gyeonggi-do, Republic of Korea.
Wei GaoSchool of Pharmaceutical Sciences and Food Engineering, Liaocheng University, Liaocheng 252059, China.
Rui LiuDepartment of Biotechnology, The University of Suwon, Hwaseong 18323, Gyeonggi-do, Republic of Korea.ORCID 0009-0007-3117-7553
Kang LeiSchool of Pharmaceutical Sciences and Food Engineering, Liaocheng University, Liaocheng 252059, China.ORCID 0000-0002-0235-5281

Funding

China Postdoctoral Science Foundation 2020M671984National Natural Science Foundation of China 31701827National Natural Science Foundation of China 32402430Natural Science Foundation of Shandong Province ZR2023MC095
6 · The paper itself

Abstract

To identify fungicide lead compounds with novel scaffold and high efficacy, a library of 4,5-dihydrotetrazolo [1,5-a]thieno [2,3-e]pyridine derivatives, consisting of 10 newly synthesized compounds and 12 previously reported compounds, was evaluated for their potential as fungicide agents. In vitro bioassay results indicated that some target compounds exhibited certain antifungal activity against the tested fungi at a concentration of 50 μg/mL. Especially, compounds

Indexed as

4,5,6,7-tetrahydrothieno [3,2-b] pyridine4,5-dihydrotetrazolo [1,5-a]thieno [2,3-e]pyridinefungicidesmode of action

Identifiers

PMID40732097
PMCPMC12300993

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.