Evidence map›Paper›PMID 40732661›Full record

ArticlePathogens (Basel, Switzerland)2025

Antibacterial Evaluation of Tricyclic Antidepressants Against

Vitória Pessoa de Farias Cabral, Daniel Sampaio Rodrigues, Lívia Gurgel do Amaral Valente Sá, Lara Elloyse Almeida Moreira, Cecília Rocha da Silva, João Batista de Andrade Neto, Érica Rayanne Mota da Costa, Thais Lima Ferreira, Leilson Carvalho de Oliveira, Beatriz Oliveira de Souza and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pathogens (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Vitória Pessoa de Farias CabralSchool of Pharmacy, Laboratory for Bioprospection of Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza 60430-372, CE, Brazil.ORCID 0000-0002-6408-7200
Daniel Sampaio RodriguesSchool of Pharmacy, Laboratory for Bioprospection of Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza 60430-372, CE, Brazil.ORCID 0000-0001-8496-8243
Lívia Gurgel do Amaral Valente SáSchool of Pharmacy, Laboratory for Bioprospection of Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza 60430-372, CE, Brazil.ORCID 0000-0002-0619-2782
Lara Elloyse Almeida MoreiraSchool of Pharmacy, Laboratory for Bioprospection of Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza 60430-372, CE, Brazil.
Cecília Rocha da SilvaSchool of Pharmacy, Laboratory for Bioprospection of Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza 60430-372, CE, Brazil.ORCID 0000-0003-4964-351X
João Batista de Andrade NetoSchool of Pharmacy, Laboratory for Bioprospection of Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza 60430-372, CE, Brazil.
Érica Rayanne Mota da CostaSchool of Pharmacy, Laboratory for Bioprospection of Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza 60430-372, CE, Brazil.ORCID 0000-0003-1430-1747
Thais Lima FerreiraSchool of Pharmacy, Laboratory for Bioprospection of Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza 60430-372, CE, Brazil.ORCID 0000-0003-0971-1311
Leilson Carvalho de OliveiraSchool of Pharmacy, Laboratory for Bioprospection of Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza 60430-372, CE, Brazil.
Beatriz Oliveira de SouzaSchool of Pharmacy, Laboratory for Bioprospection of Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza 60430-372, CE, Brazil.
Dávylla Rênnia Saldanha PinheiroSchool of Pharmacy, Laboratory for Bioprospection of Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza 60430-372, CE, Brazil.ORCID 0000-0001-6384-5754
Bruno Coêlho CavalcantiCenter for Drug Research and Development (NPDM), Federal University of Ceará, Fortaleza 60430-275, CE, Brazil.
Islay Lima MagalhãesCenter for Drug Research and Development (NPDM), Federal University of Ceará, Fortaleza 60430-275, CE, Brazil.
Manoel Odorico de MoraesCenter for Drug Research and Development (NPDM), Federal University of Ceará, Fortaleza 60430-275, CE, Brazil.
Hélio Vitoriano Nobre JúniorSchool of Pharmacy, Laboratory for Bioprospection of Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza 60430-372, CE, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The resistance of

Indexed as

Anti-Bacterial AgentsAntidepressive Agents, TricyclicStaphylococcus aureusAmitriptylineClomipramineDrug SynergismHumansMicrobial Sensitivity TestsNortriptylineOxacillinAmitriptylineAnti-Bacterial AgentsAntidepressive Agents, TricyclicClomipramineNortriptylineOxacillinamitriptylineantibacterialclomipraminemechanism of actionnortriptylineStaphylococcus aureussynergismtricyclic antidepressants

Identifiers

PMID40732661
PMCPMC12299878

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.