Evidence map›Paper›PMID 40732772›Full record

ArticlePolymers2025

Injectable PEG-PCL-PEG Copolymers for Skin Rejuvenation: In Vitro Cell Studies to in Vivo Collagen Induction.

Seunghwa Lee, Aram Kim, Jimo Koo, Yunsik Kim, Sunglim Choi, Jin Cheol Cho

Abstract read
In one paragraph

Article in Polymers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Seunghwa LeeR&D Center, CHA Meditech. Co., Ltd., 119 Techno 2-ro, Yuseong-gu, Daejeon 34116, Republic of Korea.ORCID 0000-0002-1240-3873
Aram KimDepartment of Biomedical Science, School of Medicine, CHA University, Seongnam 13488, Republic of Korea.ORCID 0000-0002-5458-1985
Jimo KooResearch & Development Center, CHA Advanced Research Institute, Seongnam 13488, Republic of Korea.
Yunsik KimConsumer Health 2 Center, CHA Advanced Research Institute, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam 13496, Republic of Korea.
Sunglim ChoiR&D Center, CHA Meditech. Co., Ltd., 119 Techno 2-ro, Yuseong-gu, Daejeon 34116, Republic of Korea.ORCID 0000-0003-0667-9774
Jin Cheol ChoR&D Center, CHA Meditech. Co., Ltd., 119 Techno 2-ro, Yuseong-gu, Daejeon 34116, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we designed an injectable skin-rejuvenating formulation based on polyethylene glycol-polycaprolactone-polyethylene glycol (PEG-PCL-PEG) copolymers to provide a synergistic combination of biocompatibility, antioxidative capacity, and regenerative potential. Through the systematic optimization of the precursor molar ratio and molecular weight, well-defined PEG-PCL-PEG copolymers were synthesized and structurally characterized using gel permeation chromatography (GPC), proton nuclear magnetic resonance (

Indexed as

antioxidant activitycollagen regenerationidebenonePEG-PCL-PEG copolymersskin rejuvenationsolubilization

Identifiers

PMID40732772
PMCPMC12300825

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.