Evidence mapPaperPMID 40732899Full record

ArticleNutrients2025

Anti-Obesity Effect of Liposomal Suspension and Extracts of

Luis Edwardo Palomo-Martínez, Norma Paniagua-Castro, Gerardo Norberto Escalona-Cardoso, Diana E Leyva-Daniel, Miguel A A Ibañez-Hernández, Yair Cruz-Narvaez, Liliana Alamilla-Beltrán

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Article in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Luis Edwardo Palomo-MartínezInstituto Politécnico Nacional, Departamento de Ingeniería Bioquímica, Escuela Nacional de Ciencias Biológicas, Av. Wilfrido Massieu 399, U. P. Adolfo López Mateos, Gustavo A. Madero 07738, Mexico.ORCID 0009-0003-1069-0666
Norma Paniagua-CastroInstituto Politécnico Nacional, Departamento de Fisiología, Escuela Nacional de Ciencias Biológicas, Av. Wilfrido Massieu 399, U. P. Adolfo López Mateos, Gustavo A. Madero 07738, Mexico.
Gerardo Norberto Escalona-CardosoInstituto Politécnico Nacional, Departamento de Fisiología, Escuela Nacional de Ciencias Biológicas, Av. Wilfrido Massieu 399, U. P. Adolfo López Mateos, Gustavo A. Madero 07738, Mexico.
Diana E Leyva-DanielInstituto Politécnico Nacional, Departamento de Ingeniería Bioquímica, Escuela Nacional de Ciencias Biológicas, Av. Wilfrido Massieu 399, U. P. Adolfo López Mateos, Gustavo A. Madero 07738, Mexico.
Miguel A A Ibañez-HernándezInstituto Politécnico Nacional, Departamento de Bioquímica, Escuela Nacional de Ciencias Biológicas, Manuel Carpio y Plan de Ayala, Casco de Santo Tomás, Miguel Hidalgo 11340, Mexico.
Yair Cruz-NarvaezInstituto Politécnico Nacional, Departamento de Ingeniería Química, Escuela Superior de Ingeniería Químicas e Industrial Extractivas, Av. Luis Enrique Erro, 399, U.P. Adolfo López Mateos, Gustavo A. Madero 07738, Mexico.ORCID 0000-0003-0956-645X
Liliana Alamilla-BeltránInstituto Politécnico Nacional, Departamento de Ingeniería Bioquímica, Escuela Nacional de Ciencias Biológicas, Av. Wilfrido Massieu 399, U. P. Adolfo López Mateos, Gustavo A. Madero 07738, Mexico.ORCID 0000-0002-0901-5140

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesObesity is the primary risk factor for the development of chronic degenerative diseases. Multidisciplinary treatments target multiple pathologies associated with obesity. In this study, a potential adjuvant therapy was evaluated by combining extracts from Hibiscus

methodsIn this research, the use of biotechnological approaches for the development of a liposomal suspension formulation with appropriate characteristics of stability, particle size, polydispersity index, concentration, and zeta potential induced an effective reduction in body weight and epididymal fat in a murine obesity model over 8 and 45 days.

resultsTreatment with the liposomal suspension reduced variables in the lipid profile, aspartate aminotransferase activity, and energy expenditure, while also promoting an increase in locomotor activity.

conclusionsTherefore, it is suggested that the liposomal suspension represents an alternative for obesity treatment and the reduction of cardiovascular risks.

Indexed as

Anti-Obesity AgentsHibiscusObesityPlant ExtractsZingiber officinaleAnimalsDiet, High-FatDisease Models, AnimalEnergy MetabolismLiposomesMaleMiceSuspensionsAnti-Obesity AgentsLiposomesPlant ExtractsSuspensionsHibiscus sabdariffaliposomal suspensionobesitypolyphenolsZingiber officinale

Identifiers

PMID40732899
PMCPMC12299839

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.